Date published: 2025-9-10

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Glyoxalase I 抗体 (6F10): sc-101537

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说明书
  • Glyoxalase I 抗体 6F10 是大鼠单克隆 IgG2b, 在5篇文献中引用,提供 200 µg/ml
  • 针对全长Glyoxalase I(源自mouse
  • 推荐用于 mouse, rat, human 和 monkey 来源的Glyoxalase I WB, IP, IF 和 ELISA检测
  • 目前,我们还没有完成Glyoxalase I 抗体 (6F10)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

在葡萄糖降解产物(GDP)的解毒过程中,乙二醛途径发挥着重要作用。乙二醛酶I(GLO1)是乙二醛酶家族的一员,在消除GDP方面非常有效。小鼠脑中乙二醛酶I的过度表达或沉默表明乙二醛酶I与焦虑之间存在关联。乙二醛酶I在基因组中的两个等位基因上产生三种异构体,形成两个同源二聚体和一个异源二聚体,每个亚基结合一个锌离子。研究表明,GLO1基因的表达在结肠癌中被诱导。在GLO1基因的启动子区域中,已经鉴定出了胰岛素应答元件(IRE)和锌金属应答元件(MRE)。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Glyoxalase I 抗体 (6F10) 参考文献:

  1. 癌症化疗中的糖醛酸酶 I 抑制剂。  |  Creighton, DJ., et al. 2003. Biochem Soc Trans. 31: 1378-82. PMID: 14641067
  2. 动脉粥样硬化中的甲基乙二醛和乙二醛酶 I  |  Hanssen, NM., et al. 2014. Biochem Soc Trans. 42: 443-9. PMID: 24646258
  3. 血管疾病中的乙二醛酶 I (Glo1) 及其代谢物。  |  Wortmann, M., et al. 2014. Biochem Soc Trans. 42: 528-33. PMID: 24646273
  4. 糖醛酸酶-I 抑制剂的最新进展。  |  Al-Balas, QA., et al. 2019. Mini Rev Med Chem. 19: 281-291. PMID: 30306863
  5. 糖醛酸酶 I-4 在 NAC72 的下游发挥作用,调节葡萄的霜霉病抗性。  |  Li, T., et al. 2021. Plant J. 108: 394-410. PMID: 34318550
  6. 作为乙二醛酶 I 抑制剂的 1,4-苯磺酰胺衍生物的设计、合成和生物学评价。  |  Audat, SA., et al. 2022. Drug Des Devel Ther. 16: 873-885. PMID: 35378924
  7. 糖醛酸酶 I 的活性影响拟南芥对铵盐营养的敏感性。  |  Borysiuk, K., et al. 2022. Plant Cell Rep. 41: 2393-2413. PMID: 36242617
  8. 三苯基二氯化铋可抑制人乙二醛酶 I 并诱导培养的癌细胞株产生细胞毒性。  |  Takasawa, R., et al. 2022. J Toxicol Sci. 47: 539-546. PMID: 36450498
  9. 家猫出生后发育过程中体细胞和精原睾丸细胞中乙二醛酶 I 和 II 的作用。  |  Braun, BC. and Müller, K. 2023. Theriogenology. 197: 10-15. PMID: 36462331
  10. 糖醛酸酶 I 是预防代谢紊乱的新靶点。  |  Miranda, ER. and Haus, JM. 2023. Pharmacol Ther. 250: 108524. PMID: 37722607

订购信息

产品名称产品编号规格价格数量收藏夹

Glyoxalase I 抗体 (6F10)

sc-101537
200 µg/ml
$316.00

Are there any issues with using sc-101537: Glyoxalase I (6F10) mouse monoclonal primary antibody on mouse samples?

Asked by: DefinitelyNotMatt
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-101537 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
Date published: 2013-10-30
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Glyoxalase I 抗体 (6F10) is rated 4.0 out of 5 by 1.
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