Date published: 2025-9-7

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GAD-67 抗体 (A-4): sc-390383

5.0(2)
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说明书
  • GAD-67抗体(A-4)是小鼠单克隆IgG3 κ, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的GAD-67的N-terminus的氨基酸4-31之间
  • 推荐用于 mouse, rat 和 human 来源的GAD-67 WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: bovine
  • 看 GAD-67 (F-6): sc-28376,可查看有标记的 GAD-67 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG3 BP-HRP是GAD-67 Antibody (A-4) 适用于 WB 应用。 的首选辅助检测试剂,该试剂现与GAD-67 Antibody (A-4) 搭配使用(请参阅下面的订购信息)。

快捷链接

関連項目

大脑中存在两种形式的谷氨酸脱羧酶(GADs):GAD-65(也称为GAD2)和GAD-67(也称为GAD1、GAD或SCP)。GAD-65和GAD-67是II型脱羧酶家族蛋白的成员,负责催化L-谷氨酸产生GABA(γ-氨基丁酸)的限速步骤。尽管两种GADs都存在于大脑中,但GAD-65定位于神经末梢的突触囊泡膜上,而GAD-67则分布于整个细胞中。GAD-67负责GABA合成的基础水平。在神经传递中对GABA需求增加的情况下,GAD-65会短暂激活以协助GABA的产生。GAD-65的缺失是有害的,可能会损害GABA的神经传递,但GAD-67的缺失是致命的。由于选择性剪接,GAD-67存在两种异构体,即主要的GAD-67形式和次要的GAD-25形式。GAD-25不在大脑中表达,但可以在各种内分泌组织中找到。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

GAD-67 抗体 (A-4)

sc-390383
200 µg/ml
$316.00

GAD-67 (A-4): m-IgG3 BP-HRP 套装

sc-550478
200 µg Ab; 40 µg BP
$354.00

GAD-67 (A-4) 中和勝肽

sc-390383 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-390383 P appropriate for?

Asked by: jerojero
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Nice productThe GAD-67 Antibody (A-4): sc-390383 works well for Western blotting applications, showing strong signal with minimal background.
Date published: 2017-02-09
Rated 5 out of 5 by from Satisfactory Western blot data of GADSatisfactory Western blot data of GAD-67 expression in non-transfected and human GAD-67 transfected 293T whole cell lysates and mouse brain tissue extract . -SCBT QC
Date published: 2013-12-27
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GAD-67 抗体 (A-4) is rated 5.0 out of 5 by 2.
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