Fluconazole-d4 (CAS 1124197-58-5)
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Fluconazole-d4 is a deuterated version of fluconazole, which is often utilized in research applications as an internal standard for the quantification of fluconazole through various analytical techniques such as mass spectrometry. The incorporation of deuterium, a stable isotope of hydrogen, into the fluconazole molecule allows for a minimal structural alteration that provides a means to differentiate the labeled compound from its non-labeled counterpart during analysis. Researchers employ fluconazole-d4 in studies to investigate the absorption, distribution, metabolism, and excretion of fluconazole. By using fluconazole-d4, scientists can achieve more accurate measurements and better understand the behavior of fluconazole in biological systems. Its role in research is critical for ensuring accurate and precise data collection in experimental applications where quantification and tracking of molecules are required.
Fluconazole-d4 (CAS 1124197-58-5) References
- A rapid and sensitive LC-MS/MS method for determination of fluconazole in human plasma and its application in infants with Candida infections. | Wu, D., et al. 2009. Ther Drug Monit. 31: 703-9. PMID: 19745791
- Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography-tandem mass spectrometry. | Chen, ZF., et al. 2012. Anal Bioanal Chem. 404: 3175-88. PMID: 23052884
- Determination of azole fungicides in atmospheric samples collected in the Canadian prairies by LC/MS/MS. | Raina, R. and Smith, E. 2012. J AOAC Int. 95: 1350-6. PMID: 23175965
- Biocides in the Yangtze River of China: spatiotemporal distribution, mass load and risk assessment. | Liu, WR., et al. 2015. Environ Pollut. 200: 53-63. PMID: 25697474
- A rapid UPLC-MS/MS assay for the simultaneous measurement of fluconazole, voriconazole, posaconazole, itraconazole, and hydroxyitraconazole concentrations in serum. | Basu, SS., et al. 2017. Clin Chem Lab Med. 55: 836-844. PMID: 27866173
- Residue dissipation and risk assessment of tebuconazole, thiophanate-methyl and its metabolite in table grape by liquid chromatography-tandem mass spectrometry. | Dong, B., et al. 2018. Food Chem. 260: 66-72. PMID: 29699683
- Response to Fungal Dysbiosis by Gut-Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease. | Li, X., et al. 2018. Cell Host Microbe. 24: 847-856.e4. PMID: 30503509
- Removal of steroid hormones and biocides from rural wastewater by an integrated constructed wetland. | Chen, J., et al. 2019. Sci Total Environ. 660: 358-365. PMID: 30640104
- Occurrence, fate and risk assessment of biocides in wastewater treatment plants and aquatic environments in Thailand. | Juksu, K., et al. 2019. Sci Total Environ. 690: 1110-1119. PMID: 31470474
- A sensitive method for analyzing fluconazole in extremely small volumes of neonatal serum. | Saito, J., et al. 2020. J Pharm Health Care Sci. 6: 14. PMID: 32626595
- Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO: a case report. | Dhanani, JA., et al. 2021. Int J Antimicrob Agents. 58: 106431. PMID: 34520832
- HIV-antiretrovirals in river water from Gauteng, South Africa: Mixed messages of wastewater inflows as source. | Horn, S., et al. 2022. Sci Total Environ. 806: 150346. PMID: 34601177
- UHPLC-HRMS Method for the Simultaneous Screening of 235 Drugs in Capillary Blood for Doping Control Purpose: Comparative Evaluation of Volumetric and Non-volumetric Dried Blood Spotting Devices. | Mazzarino, M., et al. 2022. ACS Omega. 7: 31845-31868. PMID: 36119994
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fluconazole-d4, 1 mg | sc-218490 | 1 mg | $406.00 |