Date published: 2025-9-7
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FIH-1 Antibody (D-12) - Western Blotting - Image 356111
FIH-1 抗体 (D-12): sc-365016. Jurkat (A), A-375 (B), HL-60 (C), HEK293 (D), Raji (E) 和 A-431 (F) 全细胞裂解液中 FIH-1 表达的 Western 印迹分析.
FIH-1 抗体 (D-12): sc-365016. Jurkat (A), A-375 (B), HL-60 (C), HEK293 (D), Raji (E) 和 A-431 (F) 全细胞裂解液中 FIH-1 表达的 Western 印迹分析.

FIH-1 抗体 (D-12): sc-365016

5.0(3)
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说明书
  • FIH-1抗体(D-12)是小鼠单克隆IgG1 (kappa轻链)，规格为200 µg/ml
  • 针对human起源的FIH-1内部区域内的氨基酸15-243进行
  • 推荐用于 mouse, rat 和 human 来源的FIH-1 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG1 BP-HRP是FIH-1 Antibody (D-12) for WB applications. 的首选辅助检测试剂，这些试剂现与FIH-1 Antibody (D-12) 打包提供（请参阅下面的订购信息）。

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    描述
    基因信息
    蛋白序列
    说明书与实验方案
    研究信息

    関連項目

    抑制HIF-1的因子（FIH-1）以同二聚体的形式存在，并与HIF-1α结合。具体而言，FIH-1作为天冬酰胺羟化酶发挥作用。它催化HIF-1α羧基末端转录激活结构域内天冬酰胺残基803的β-碳的羟化。这种羟化事件阻断了HIF-1α与辅激活子的结合。FIH-1还与von Hippel-Lindau（VHL）肿瘤抑制蛋白结合，后者抑制HIF-1α的转录活性。在瞬时转染的人骨肉瘤细胞中，FIH-1定位于细胞质中。FIH-1的结构包括一个含有铁结合三联体残基的果冻卷状β-桶。编码人FIH-1的基因位于染色体10q24。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    FIH-1 抗体 (D-12)

    sc-365016
    200 µg/ml
    		$316.00

    FIH-1 (D-12): m-IgG Fc BP-HRP 套装

    sc-540300
    200 µg Ab; 10 µg BP
    		$354.00

    FIH-1 (D-12): m-IgG1 BP-HRP 套装

    sc-542023
    200 µg Ab; 20 µg BP
    		$354.00

    I need to use an antibody to detect the protein in samples of avian origin. Do you know if sc-365016: FIH-1 (D-12) mouse monoclonal antibody will work?

    Asked by: jenniferc
    Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
    Answered by: Technical Support
    Date published: 2017-03-06
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    Rated 5 out of 5 by from For tasksThe aim of our study was to explore the inhibitory factor HIF-1 as a homodimer and to bind to HIF-1α, which catalyzes the hydroxylation of HIF-1α. We use it to complete the task
    Date published: 2017-02-09
    Rated 5 out of 5 by from Produced positive Western Blot data of FIHProduced positive Western Blot data of FIH-1 expression in Jurkat whole cell lysate. -SCBT QC
    Date published: 2015-04-19
    Rated 5 out of 5 by from Produced positive Western Blot data of FIHProduced positive Western Blot data of FIH-1 expression in human skeletal muscle tissue extract. -SCBT QC
    Date published: 2014-08-11
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    FIH-1 抗体 (D-12) is rated 5.0 out of 5 by 3.
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