Date published: 2025-9-9

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Ferrochelatase 抗体 (D-7): sc-271434

5.0(2)
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说明书
  • Ferrochelatase抗体(D-7)是小鼠单克隆IgG2b κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列124-423位于human物种的Ferrochelatase的C-terminus
  • 推荐用于 human 来源的mitochondrial precursor and mature Ferrochelatase WB, IP, IF 和 ELISA检测
  • 看 Ferrochelatase (A-3): sc-377377,可查看有标记的 Ferrochelatase 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是Ferrochelatase Antibody (D-7) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Ferrochelatase Antibody (D-7) 打包提供(请参阅下面的订购信息)。

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関連項目

亚铁螯合酶,也称为血红素合成酶或原卟啉铁裂解酶,是原血红素生物合成的末端酶,催化亚铁形式的铁插入原卟啉IX中。成熟的亚铁螯合酶是一种同源二聚体、线粒体膜相关蛋白,在N端54个氨基酸转运肽的下游翻译。亚铁螯合酶含有两个一氧化氮(NO)敏感簇和协调的2FE-2S簇,它们可能潜在地作为一氧化氮传感器。编码亚铁螯合酶的FECH基因的缺陷会引起红细胞生成性原卟啉病(EPP),这是一种以光敏感性和肝胆疾病为特征的主要遗传性卟啉代谢疾病。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Ferrochelatase 抗体 (D-7) 参考文献:

  1. 底物与人类铁螯合酶的相互作用  |  Medlock, A., et al. 2007. Proc Natl Acad Sci U S A. 104: 1789-93. PMID: 17261801
  2. 铁螯合酶是眼部新生血管的治疗靶点。  |  Basavarajappa, HD., et al. 2017. EMBO Mol Med. 9: 786-801. PMID: 28377496
  3. 铁螯合酶调节视网膜新生血管  |  Pran Babu, SPS., et al. 2020. FASEB J. 34: 12419-12435. PMID: 32716567
  4. 铁螯合酶小分子抑制剂是一种抗血管生成药物。  |  Sishtla, K., et al. 2022. Cell Chem Biol. 29: 1010-1023.e14. PMID: 35090600
  5. 铁螯合酶:绘制线粒体中铁和卟啉代谢的交叉图。  |  Obi, CD., et al. 2022. Front Cell Dev Biol. 10: 894591. PMID: 35646904
  6. 红细胞和非红细胞中铁螯合酶相互作用组的蛋白质组学分析  |  Obi, CD., et al. 2023. Life (Basel). 13: PMID: 36836934
  7. 谷氨酸脱氢酶与铁螯合酶结合作为抗结核药物诱发肝损伤的生物标志物  |  He, B., et al. 2023. Br J Clin Pharmacol. 89: 3092-3104. PMID: 37259680
  8. 铁插入共卟啉 III-铁螯合酶复合物:中间扭曲催化物种的证据。  |  Gabler, T., et al. 2023. Protein Sci. 32: e4788. PMID: 37743577
  9. 铁螯合酶的结构和功能。  |  Ferreira, GC., et al. 1995. J Bioenerg Biomembr. 27: 221-9. PMID: 7592569
  10. 铁螯合酶的分子和遗传特征。  |  Taketani, S. 1993. Tohoku J Exp Med. 171: 1-20. PMID: 8122254

订购信息

产品名称产品编号规格价格数量收藏夹

Ferrochelatase 抗体 (D-7)

sc-271434
200 µg/ml
$316.00

Ferrochelatase (D-7): m-IgGκ BP-HRP 套装

sc-534960
200 µg Ab; 40 µg BP
$354.00

Ferrochelatase (D-7): m-IgG2b BP-HRP 套装

sc-549321
200 µg Ab; 10 µg BP
$354.00

What is the recommended starting dilution for Western blot for sc-271434: Ferrochelatase (D-7) monoclonal antibody?

Asked by: DefinitelyNotMatt
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by from Nice Western Blot data of FerrochelataseNice Western Blot data of Ferrochelatase expression in K-562 and HEL 92. -SCBT QC
Date published: 2015-05-09
Rated 5 out of 5 by from Satisfactory Western Blot data of FerrochelataseSatisfactory Western Blot data of Ferrochelatase expression in Jurkat whole cell lysate. -SCBT QC
Date published: 2014-09-14
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Ferrochelatase 抗体 (D-7) is rated 5.0 out of 5 by 2.
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