Epicoccamide (CAS 606139-26-8)
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Epicoccamide is a compound that functions as a potent inhibitor of the enzyme phosphatidylinositol 3-kinase (PI3K). It exerts its mechanism of action by targeting the catalytic subunit of PI3K, thereby disrupting the signaling pathway involved in cell growth, proliferation, and survival. By inhibiting PI3K, epicoccamide interferes with the activation of downstream effectors such as Akt, leading to the suppression of various cellular processes. Epicoccamide′s mechanism of action involves binding to the ATP-binding pocket of PI3K, preventing the phosphorylation of phosphatidylinositol 4,5-bisphosphate (PIP2) to phosphatidylinositol 3,4,5-trisphosphate (PIP3). As a result, epicoccamide plays a role in modulating intracellular signaling cascades and has the potential to impact various cellular functions in experimental applications.
Epicoccamide (CAS 606139-26-8) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Epicoccamide, 1 mg | sc-391530 | 1 mg | $255.00 |