EDTA, disodium salt, dihydrate, for molecular biology CAS: 6381-92-6
MF: C10H14N2Na2O8·2H2O
MW: 372.24
A chelating agent and inhibitor of metalloproteases.

EDTA, disodium salt, dihydrate, for molecular biology (CAS 6381-92-6)

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同义词: Edetate disodium salt dihydrate
应用; A chelating agent and inhibitor of metalloproteases
CAS号码: 6381-92-6
纯度: ≥99%
分子量: 372.24
分子式: C10H14N2Na2O8·2H2O
* 参考分析证明 大量特定数据 (包括水 含量).
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EDTA, disodium salt, dihydrate, for molecular biology is extensively used as a chelator of divalent cations such as Ca2+. EDTA (Ethylenediaminetetraacetic acid) is a chelating agent, a general chemical, and a sequestrant. In molecular biology applications, addition of EDTA minimizes the impact of metal ion contaminants. Also used to facilitate enzymatic reactions that could be inhibited by heavy metal traces. It also inhibits enzymes, such as metalloproteases, which require divalent cations for activity. EDTA, disodium salt, dihydrate, for molecular biology is an inhibitor of Calpain.


参考文献

1. Van Kley, H. and Claywell, C.S. 1973. Clin. Chem. 19: 621-623. PMID: 4196140
2. Bhargava, K.K. and Acharya, S.A. 1989. Semin Nucl Med. 19: 187-201. PMID: 2503873
3. Brandt, K.D., et al. 1991. Bioconjug. Chem. 2: 67-70. PMID: 1908706
4. Jasin, H.E. and Taurog, J.D. 1991. J. Clin. Invest. 87: 1531-1536. PMID: 1708782
5. Lauer, S.A. and Nolan, J.P. 2002. Cytometry. 48: 136-145. PMID: 12116359

外观 :
Powder
物理状态 :
Solid
溶解度 :
Soluble in water (~100 g/l) at 20° C, (95%) alcohol (Slightly soluble), and 3 M NaOH (100 mg/mL).
保存 :
Store at room temperature
熔点 :
248° C
折射率 :
n20D 1.36
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
2
RTECS :
AH4410000
PubChem CID :
636371
默克索引 :
14: 3517
MDL 号码 :
MFCD00150037
EC号码 :
205-358-3
Beilstein 注册 :
3900609
SMILES :
C(CN(CC(=O)O)CC(=O)[O-])N(CC(=O)O)CC(=O)[O-].O.O.[Na+].[Na+]

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