Date published: 2025-10-10

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Ebi2 抗体 (G-12): sc-514342

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说明书
  • Ebi2 抗体 G-12 是小鼠单克隆 IgG2a (kappa轻链),Ebi2抗体,规格为200 µg/ml
  • 特异性抗原位于human物种的Ebi2的N-terminus的氨基酸1-24之间
  • Ebi2 抗体 (G-12) 推荐用于WB, IP, IF 和 ELISA,检测human 来源的 Ebi2
  • 抗Ebi2抗体(G-12)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRP是Ebi2 Antibody (G-12) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Ebi2 Antibody (G-12) 打包提供(请参阅下面的订购信息)。

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関連項目

Ebi2抗体(G-12)是一种IgG2a κ型小鼠单克隆Ebi2抗体(也被称为Ebi2抗体),可通过WB、IP、IF和ELISA等方法检测人类来源的Ebi2蛋白。Ebi2抗体(G-12)既有非偶联形式的抗Ebi2抗体,也有多种偶联形式的抗Ebi2抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Epstein-Barr病毒诱导基因2(Ebi2)是一种含有357个氨基酸的多通道膜蛋白。它表达于B淋巴细胞和淋巴组织中,可能具有调节免疫系统的作用。在Epstein-Barr病毒诱导的九个基因中,Ebi2的上调水平最高。Ebi2是一种G蛋白偶联受体,通过G蛋白Gαi发出信号。Ebi2含有七个疏水跨膜区域,其细胞外N末端有一个推测的N-连接糖基化位点。Ebi2被认为参与调节Epstein-Barr病毒对B淋巴细胞的影响。此外,Ebi2可能在介导正常淋巴细胞功能方面发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Ebi2 抗体 (G-12) 参考文献:

  1. NF-kappa B 在表达潜伏膜蛋白 1 或 Epstein-Barr 病毒潜伏期 III 感染细胞的存活和转录中的作用。  |  Cahir-McFarland, ED., et al. 2004. J Virol. 78: 4108-19. PMID: 15047827
  2. Epstein-Barr 病毒潜伏抗原 3C 可通过 SCF 细胞泛素连接酶介导视网膜母细胞瘤蛋白的降解。  |  Knight, JS., et al. 2005. Proc Natl Acad Sci U S A. 102: 18562-6. PMID: 16352731
  3. EBI2 的分子药理学表型。一种具有组成型活性的孤儿七跨膜受体。  |  Rosenkilde, MM., et al. 2006. J Biol Chem. 281: 13199-13208. PMID: 16540462
  4. Epstein-Barr 病毒与多发性硬化症。  |  Lünemann, JD. and Münz, C. 2007. Curr Neurol Neurosci Rep. 7: 253-8. PMID: 17488592
  5. 氧固醇-EBI2信号在免疫调节和病毒感染中的作用。  |  Daugvilaite, V., et al. 2014. Eur J Immunol. 44: 1904-12. PMID: 24810762
  6. EBI2调节人类星形胶质细胞的细胞内信号传导和迁移。  |  Rutkowska, A., et al. 2015. Glia. 63: 341-51. PMID: 25297897
  7. EBI2调节星形胶质细胞中的促炎信号传导和细胞因子释放。  |  Rutkowska, A., et al. 2018. Neuropharmacology. 133: 121-128. PMID: 29374507
  8. 脾脏和局部免疫反应以及自身免疫中的EBI2。  |  Barington, L., et al. 2018. J Leukoc Biol. 104: 313-322. PMID: 29741800
  9. 氧固醇传感器EBI2/GPR183的结构,它是免疫反应的关键调节因子。  |  Chen, H., et al. 2022. Structure. 30: 1016-1024.e5. PMID: 35537452
  10. 氧固醇受体EBI2连接先天性和适应性免疫,以限制干扰素反应和系统性红斑狼疮。  |  Zhang, F., et al. 2023. Adv Sci (Weinh). 10: e2207108. PMID: 37469011
  11. 鼻息肉EBI2+抗体分泌细胞的自身反应性和成熟度增加。  |  Bai, J., et al. 2024. JCI Insight. 9: PMID: 39253973
  12. Epstein-Barr 病毒诱导基因:首个淋巴细胞特异性 G 蛋白偶联肽受体。  |  Birkenbach, M., et al. 1993. J Virol. 67: 2209-20. PMID: 8383238

订购信息

产品名称产品编号规格价格数量收藏夹

Ebi2 抗体 (G-12)

sc-514342
200 µg/ml
$316.00

Ebi2 (G-12): m-IgG Fc BP-HRP 套装

sc-526361
200 µg Ab; 10 µg BP
$354.00

Ebi2 (G-12): m-IgG2a BP-HRP 套装

sc-546605
200 µg Ab; 10 µg BP
$354.00

Ebi2 抗体 (G-12) AC

sc-514342 AC
500 µg/ml, 25% agarose
$416.00

Ebi2 抗体 (G-12) HRP

sc-514342 HRP
200 µg/ml
$316.00

Ebi2 抗体 (G-12) FITC

sc-514342 FITC
200 µg/ml
$330.00

Ebi2 抗体 (G-12) PE

sc-514342 PE
200 µg/ml
$343.00

Ebi2 抗体 (G-12) Alexa Fluor® 488

sc-514342 AF488
200 µg/ml
$357.00

Ebi2 抗体 (G-12) Alexa Fluor® 546

sc-514342 AF546
200 µg/ml
$357.00

Ebi2 抗体 (G-12) Alexa Fluor® 594

sc-514342 AF594
200 µg/ml
$357.00

Ebi2 抗体 (G-12) Alexa Fluor® 647

sc-514342 AF647
200 µg/ml
$357.00

Ebi2 抗体 (G-12) Alexa Fluor® 680

sc-514342 AF680
200 µg/ml
$357.00

Ebi2 抗体 (G-12) Alexa Fluor® 790

sc-514342 AF790
200 µg/ml
$357.00

Ebi2 (G-12) 中和勝肽

sc-514342 P
100 µg/0.5 ml
$68.00

How do you know that the band at 90kDa is GPR183 also? 

Asked by: Miguellllll
Thank you for your question. Ebi2 of human origin is predicted to have a molecular weight of 41 kDa. In addition, according to online sources this target may go through post-translational modifications and can form a homodimer and heterodimer, which is what we may be detecting at 90 kDa. If you have additional questions, please contact Technical Support by calling 1800-457-3801 option 2, by emailing scbt@scbt.com or by live chat on our website at www.scbt.com so we may further assist you.
Answered by: Blake J
Date published: 2021-07-19

Hi I was wondering if you could provide me with a quote for Ebi2 Antibody (G-12): sc-514342 in lyophilized format (200ug total) Thanks, Anna

Asked by: akbMedimmune
Please contact our Special Orders Department to inquire about the possibility of ordering a non-standard form of an antibody. Please call our Technical Service Department, or email <specialorders@scbt.com>.
Answered by: Tech Service
Date published: 2019-06-26

What application is the blocking peptide sc-514342 P appropriate for?

Asked by: AbPolly
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great Western blot data of Ebi2 expressionGreat Western blot data of Ebi2 expression in U266 and HeLa whole cell lysates. -SCBT QC
Date published: 2013-11-05
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Ebi2 抗体 (G-12) is rated 5.0 out of 5 by 1.
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