cystatin B Antibody (6A7): sc-101510

Cystatin B Antibody (6A7) is a mouse monoclonal IgG1 antibody that detects Cystatin B in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Cystatin B, also known as PME, CST6, STFB, CPI-B, and stefin B, is a crucial thiol protease inhibitor that plays a significant role in cellular homeostasis by preventing the leakage of intracellular proteases from lysosomes, thereby protecting cells from potential damage caused by these enzymes. Anti-Cystatin B antibody (6A7) recognizes a protein predominantly expressed in vital organs such as the heart, liver, and kidney, where Cystatin B helps maintain the integrity of cellular functions and contributes to the regulation of proteolytic activity. Cystatin B′s importance extends to involvement in various physiological processes, including tissue remodeling and immune response, making Cystatin B a key player in both health and disease. Cystatin B monoclonal antibody (6A7) serves as an essential tool for researchers studying protease inhibition and its implications in pathological conditions, including neurodegenerative diseases and cancer, where dysregulation of proteolytic processes can lead to significant cellular dysfunction.

The preferred cystatin B antibody is cystatin B Antibody (F-5): sc-166561.