CYP2F2 Antibody (E-7): sc-374470

CYP2F2 Antibody (E-7) is a mouse monoclonal IgG3 antibody that detects CYP2F2 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CYP2F2 is a murine-specific membrane-bound protein predominantly localized to the endoplasmic reticulum membrane, where CYP2F2 plays a crucial role in the metabolism of potentially harmful substances. As a member of the cytochrome P450 family, CYP2F2 is involved in catalyzing redox reactions, which are essential for the detoxification of various xenobiotics, including carcinogenic pneumotoxins. Notably, CYP2F2 is responsible for converting naphthalene, a compound commonly found in mothballs, into a glutathione-dihydronaphthalene conjugate, a process that is significant due to implications in Clara cell necrosis. The polymorphic nature of CYP2F2 may influence individual sensitivity to such toxins, highlighting CYP2F2′s importance in toxicology and pharmacogenomics. Additionally, CYP2F2 serves as the murine homolog of human CYP2F1, further emphasizing CYP2F2′s relevance in comparative studies of cytochrome P450 enzymes across species. With an ability to facilitate critical metabolic processes, anti-CYP2F2 antibody (E-7) is an invaluable tool for researchers investigating the biochemical pathways associated with pulmonary toxicity and the broader implications of cytochrome P450 enzymes in health and disease.

The preferred CYP2F2 antibody is CYP2F2 Antibody (F-9): sc-374540.