Date published: 2026-6-4

1-800-457-3801

SCBT Portrait Logo
Seach Input

Clothiapine (CAS 2058-52-8)

5.0(1)
Write a reviewAsk a question

Application:
Clothiapine is a dibenzothiazepine analog of quetiapine
CAS Number:
2058-52-8
Purity:
99%
Molecular Weight:
343.87
Molecular Formula:
C18H18ClN3S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Clothiapine is structurally analogous to quetiapine (sc-219681), clothiapine is of the dibenzothiazepine chemical class. Clothiapine is an internal standard for precise and accurate HPLC detection of hyroxyzine and buprenorphine from plasma.


Clothiapine (CAS 2058-52-8) References

  1. A simple high-performance liquid chromatographic method for detection of hydroxyzine in human plasma after overdose.  |  Péhourcq, F. 2004. J Pharmacol Toxicol Methods. 50: 41-4. PMID: 15233966
  2. Unusual compulsive motor activity during treatment with clothiapine in a mentally retarded adolescent.  |  Coppola, G., et al. 2004. Brain Dev. 26: 409-11. PMID: 15275706
  3. Clothiapine in the management of schizophrenia.  |  Buchan, T., et al. 1977. S Afr Med J. 51: 237-40. PMID: 15324
  4. Determination of several psychiatric drugs in whole blood using capillary gas-liquid chromatography with nitrogen phosphorus detection: comparison of two solid phase extraction procedures.  |  Sánchez de la Torre, C., et al. 2005. Forensic Sci Int. 155: 193-204. PMID: 16226158
  5. Interaction of clozapine and its nitrenium ion with rat D2 dopamine receptors: in vitro binding and computational study.  |  Dilly, S. and Liégeois, JF. 2011. J Comput Aided Mol Des. 25: 163-9. PMID: 21184252
  6. Blockade of parabrachial pressor responses by spinal administration of an N-methyl-D-aspartic acid receptor antagonist.  |  Bazil, MK. and Gordon, FJ. 1990. Neuropharmacology. 29: 923-30. PMID: 2147741
  7. Antipsychotic drugs and the risk of ventricular arrhythmia and/or sudden cardiac death: a nation-wide case-crossover study.  |  Wu, CS., et al. 2015. J Am Heart Assoc. 4: PMID: 25713294
  8. Effectiveness of Metformin for Weight Reduction in Children and Adolescents Treated with Mixed Dopamine and Serotonin Receptor Antagonists: A Naturalistic Cohort Study.  |  Levy-Shraga, Y., et al. 2021. J Child Adolesc Psychopharmacol. 31: 376-380. PMID: 33887146
  9. Computational investigation, comparative approaches, molecular structural, vibrational spectral, non-covalent interaction (NCI), and electron excitations analysis of benzodiazepine derivatives.  |  Sarala, S., et al. 2021. J Mol Model. 27: 266. PMID: 34453612
  10. A brief history of clozapine use in Taiwan.  |  Lin, SK. and Lane, HY. 2024. Schizophr Res. 268: 34-37. PMID: 37391310
  11. Determination of buprenorphine in plasma by liquid chromatography: application to heroin-dependent subjects.  |  Lagrange, F., et al. 1998. J Pharm Biomed Anal. 16: 1295-300. PMID: 9777603

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Clothiapine, 20 mg

sc-200404
20 mg
$38.00

Clothiapine, 100 mg

sc-200404A
100 mg
$166.00