(+)-Cloprostenol CAS: 54276-21-0
MF: C22H29ClO6
MW: 424.9
A synthetic analog of prostaglandin F2&alpha.

(+)-Cloprostenol (CAS 54276-21-0)

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备用名: (+)-16-m-chlorophenoxy tetranor Prostaglandin F2α
应用; (+)-Cloprostenol is a synthetic analog of prostaglandin F2&alpha
CAS号码: 54276-21-0
分子量: 424.9
分子式: C22H29ClO6
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α), an PGF2αR (FP receptor) agonist and a potent luteolytic agent in hamsters and rats. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity.Cloprostenol is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without having the side effects associated with PGF2α.


参考文献

1 Dukes, M., Russell, W., Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α Nature 250, 330-331 (1974). 2 Serrero, G., Lepak, N.M. Prostaglandin F2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem Biophys Res Commun 233 200-202 (1997).

规划 :
A solution in ethanol
物理状态 :
Liquid
保存 :
Store at -20° C
沸点 :
78° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
5311053
SMILES :
C1[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]@H]1O)/C=C/[[email protected]](COC2=CC(=CC=C2)Cl)O)C/C=C\\CCCC(=O)O)O

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