Date published: 2025-9-5

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claudin-1 抗体 (D-4): sc-137121

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说明书
  • claudin-1抗体(D-4)是小鼠单克隆IgG1 κ, 在9篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的claudin-1的C-terminus的氨基酸168-207之间
  • 抗-claudin-1 抗体 (D-4) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 claudin-1; 也和以下物种反应,包括: 和 equine, canine and bovine
  • 抗claudin-1抗体(D-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取claudin-1 (D-4): sc-137121免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成claudin-1 抗体 (D-4)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

Claudin-1抗体(D-4)是一种IgG1 κ小鼠单克隆Claudin-1抗体,可通过WB、IP、IF和ELISA方法检测小鼠、大鼠和人类的Claudin-1。Claudin-1抗体(D-4)既可以非偶联抗Claudin-1抗体的形式提供,也可以多种偶联形式的抗Claudin-1抗体提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Claudin超家族由人类中许多结构相关的蛋白质组成。这些蛋白质是细胞旁转运中紧密连接的重要结构和功能组分。Claudins位于所有含紧密连接的组织中的上皮细胞和内皮细胞。已知有三类蛋白质定位于紧密连接,包括Claudins、Occludin和连接粘附分子。Claudins由四个跨膜结构域和两个细胞外环组成,构成紧密连接的链。Claudin的表达通常严格限制在不同组织的特定区域,并可能在通过紧密连接的跨细胞转运中发挥重要作用。Claudin-1是一种多次跨膜蛋白质,在肾脏和肝脏中高水平表达,在脾脏、心脏、大脑、肺和睾丸中表达水平较低。编码Claudin-1的基因缺陷是导致鱼鳞病-硬化性胆管炎新生儿综合征(NISCH)的原因,这是一种常染色体隐性综合征,其特征是普通型鱼鳞病、头皮毛发稀疏、瘢痕性脱发和硬化性胆管炎。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

claudin-1 抗体 (D-4)

sc-137121
200 µg/ml
$316.00

claudin-1 抗体 (D-4) AC

sc-137121 AC
500 µg/ml, 25% agarose
$416.00

claudin-1 抗体 (D-4) HRP

sc-137121 HRP
200 µg/ml
$316.00

claudin-1 抗体 (D-4) FITC

sc-137121 FITC
200 µg/ml
$330.00

claudin-1 抗体 (D-4) PE

sc-137121 PE
200 µg/ml
$343.00

claudin-1 抗体 (D-4) Alexa Fluor® 488

sc-137121 AF488
200 µg/ml
$357.00

claudin-1 抗体 (D-4) Alexa Fluor® 546

sc-137121 AF546
200 µg/ml
$357.00

claudin-1 抗体 (D-4) Alexa Fluor® 594

sc-137121 AF594
200 µg/ml
$357.00

claudin-1 抗体 (D-4) Alexa Fluor® 647

sc-137121 AF647
200 µg/ml
$357.00

claudin-1 抗体 (D-4) Alexa Fluor® 680

sc-137121 AF680
200 µg/ml
$357.00

claudin-1 抗体 (D-4) Alexa Fluor® 790

sc-137121 AF790
200 µg/ml
$357.00

claudin-1 (D-4) 中和勝肽

sc-137121 P
100 µg/0.5 ml
$68.00

I am interested in labeling cells with this antibody and make flow cytometry. Have you tested whether it works for flow

Asked by: Silvina
Thank you for your message. So far, we haven’t tested the antibody for flow cytometry.
Answered by: SCBT Heidelberg Support
Date published: 2018-11-27

What application is the blocking peptide sc-137121 P appropriate for?

Asked by: Randy McDonald
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-15
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Rated 5 out of 5 by from Good antibodyWork very well. Clean and strong signal in WB and IF.
Date published: 2020-08-18
Rated 5 out of 5 by from Publishable resultsThis antibody reacts with mouse, rat, and human and provides clear WB bands for each. It has been published with multiple times.
Date published: 2017-01-31
Rated 5 out of 5 by from Strong signal for WB in both human claudinStrong signal for WB in both human claudin-1 transfected 293T and Hep G2 whole cell lysates. -SCBT QC
Date published: 2015-05-19
Rated 5 out of 5 by from Robust band in WB in SCCRobust band in WB in SCC-4, RT-4, Hep G2 and T24 whole cell lysates. -SCBT QC
Date published: 2015-03-04
Rated 5 out of 5 by from Strong band in WB in mouse ClaudinStrong band in WB in mouse Claudin-1 transfected 293T whole cell lysate. -SCBT QC
Date published: 2013-08-16
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claudin-1 抗体 (D-4) is rated 5.0 out of 5 by 5.
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