Candesartan Celexetil Ester (CAS 145040-37-5)

物理状态 :

Solid

溶解度 :

Soluble in water (<1 mg/ml at 25° C), DMSO (122 mg/ml at 25° C), methanol, DMF (~30 mg/ml), and ethanol (4 mg/ml at 25° C).

保存 :

Store at -20° C

熔点 :

167-170° C

沸点 :

843.32° C at 760 mmHg (Predicted)

密度 :

1.37 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.67 (Predicted)

IC50 :

Angiotensin II type 1a (AT-1a) receptor: IC₅₀ = 200 nM (oryctolagus cuniculus); Cruzipain: IC₅₀ = 42 µM (trypanosoma cruzi)

pK值 :

pK_a: 4.24 (Predicted), pK_b: 3.93 (Predicted)

德国水公害等级 :

3

RTECS :

DD6672500

PubChem CID :

Merck 索引 :

14: 1739

MDL 号码 :

MFCD00871371

SMILES :

CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6