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Calgranulin B 抗体 (B-5): sc-376772

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说明书
  • Calgranulin B抗体(B-5)是小鼠单克隆IgG1 λ, 在10篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Calgranulin B的C-terminus附近的氨基酸63-99之间
  • Calgranulin B 抗体 (B-5) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 Calgranulin B
  • 抗Calgranulin B抗体(B-5)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • m-IgGλ BP-HRP(小鼠 IgGλ 结合蛋白-HRP)是Calgranulin B Antibody (B-5) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现可与Calgranulin B Antibody (B-5) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGλ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。
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Calgranulin B抗体(B-5)是一种IgG1λ小鼠单克隆Calgranulin B抗体,可通过WB、IP、IF、IHC(P)和ELISA检测人源Calgranulin B。Calgranulin B抗体(B-5)有非偶联抗Calgranulin B抗体形式,以及多种偶联形式的抗Calgranulin B抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。EF-手型钙结合蛋白家族包括Calbindin(以前称为维生素D依赖性钙结合蛋白)、S-100α和β、Calgranulin A(也称为MRP8)、Calgranulin B(也称为MRP14)和Calgranulin C(S-100样蛋白),以及小清蛋白家族成员,包括小清蛋白α和小清蛋白β(也称为癌蛋白)。 Calbindin、S-100蛋白质和小清蛋白蛋白质在神经组织中均有表达。此外,S-100α和β存在于多种其他组织中,Calbindin存在于肠和肾中。小清蛋白α也存在于快速收缩/舒张的骨骼肌纤维中,小清蛋白β存在于许多肿瘤组织和Corti器官中。 Calbindin、S-100蛋白质和小清蛋白在睾丸间质细胞和睾丸中都有检测到。这些蛋白质被认为在激素产生和精子发生中起作用。 Calgranulin在巨噬细胞和上皮细胞中表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Calgranulin B 抗体 (B-5) 参考文献:

  1. MRP8(S100A8)和MRP14(S100A9)在人类白细胞跨内皮迁移中的调节作用。  |  Kerkhoff, C., et al. 1999. Pathobiology. 67: 230-2. PMID: 10725790
  2. 改变细胞色素b558的构象状态可启动NADPH氧化酶的激活:MRP8/MRP14调节。  |  Berthier, S., et al. 2003. J Biol Chem. 278: 25499-508. PMID: 12719414
  3. 银屑病素(S100A7)和钙粘蛋白-B(S100A9)的诱导取决于活性氧,并且可通过Bcl-2和抗氧化剂下调。  |  Carlsson, H., et al. 2005. Cancer Biol Ther. 4: 998-1005. PMID: 16082188
  4. 结直肠癌患者粪便中钙粒蛋白B的评估。  |  Yoo, BC., et al. 2008. Dis Colon Rectum. 51: 1703-9. PMID: 18584251
  5. MRP14在纤维化间质性肺疾病的支气管肺泡灌洗液中升高。  |  Korthagen, NM., et al. 2010. Clin Exp Immunol. 161: 342-7. PMID: 20550547
  6. MRP14缺乏通过增加小胶质细胞的吞噬作用和调节淀粉样蛋白前体蛋白的加工来减轻淀粉样β的负担。  |  Kummer, MP., et al. 2012. J Neurosci. 32: 17824-9. PMID: 23223301
  7. MRP8/MRP14在肝内胆管癌中的诊断和预后价值。  |  Jin, GZ., et al. 2015. Oncotarget. 6: 39357-64. PMID: 26472105
  8. 甲状腺滤泡细胞中MRP14异常表达通过IL-1β/MAPK途径介导桥本氏甲状腺炎中的趋化因子分泌。  |  Luo, X., et al. 2018. Endocr Connect. 7: 850-858. PMID: 29764904
  9. 钙粒蛋白B基因在体外和体内对宫颈癌生物行为的作用[撤回]。  |  . 2022. Cancer Manag Res. 14: 1741-1742. PMID: 35607446
  10. MRP14是一种在单核细胞分化过程中表达的S100蛋白,其磷酸化可调节Ca2+依赖性从细胞质到细胞膜和细胞骨架的转运。  |  van den Bos, C., et al. 1996. J Immunol. 156: 1247-54. PMID: 8558004

订购信息

产品名称产品编号规格价格数量收藏夹

Calgranulin B 抗体 (B-5)

sc-376772
200 µg/ml
$322.00

Calgranulin B (B-5): m-IgGλ BP-HRP 套装

sc-523087
200 µg Ab, 40 µg BP
$361.00

Calgranulin B 抗体 (B-5) AC

sc-376772 AC
500 µg/ml, 25% agarose
$424.00

Calgranulin B 抗体 (B-5) HRP

sc-376772 HRP
200 µg/ml
$322.00

Calgranulin B 抗体 (B-5) FITC

sc-376772 FITC
200 µg/ml
$336.00

Calgranulin B 抗体 (B-5) PE

sc-376772 PE
200 µg/ml
$349.00

Calgranulin B 抗体 (B-5) Alexa Fluor® 488

sc-376772 AF488
200 µg/ml
$364.00

Calgranulin B 抗体 (B-5) Alexa Fluor® 546

sc-376772 AF546
200 µg/ml
$364.00

Calgranulin B 抗体 (B-5) Alexa Fluor® 594

sc-376772 AF594
200 µg/ml
$364.00

Calgranulin B 抗体 (B-5) Alexa Fluor® 647

sc-376772 AF647
200 µg/ml
$364.00

Calgranulin B 抗体 (B-5) Alexa Fluor® 680

sc-376772 AF680
200 µg/ml
$364.00

Calgranulin B 抗体 (B-5) Alexa Fluor® 790

sc-376772 AF790
200 µg/ml
$364.00

Calgranulin B (B-5) 中和勝肽

sc-376772 P
100 µg/0.5 ml
$69.00

What application is the blocking peptide sc-376772 P appropriate for?

Asked by: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by 2017zzzz121221 from Goodgood antibody good antibody good antibody good antibody
Date published: 2025-11-25
Rated 1 out of 5 by rusiario from Not workingNo band detected from whole cell lysates of high grade serous ovarian cancer cells.
Date published: 2024-07-09
Rated 5 out of 5 by fatulous from excellentthis antibody exhibits positive results in our experiment, without non-specific staining
Date published: 2017-10-31
Rated 5 out of 5 by xiaowantong from excellentwe apply this antibody into western blot and ICC, it performs very well in these two experiments.
Date published: 2017-07-15
Rated 5 out of 5 by Trav11 from Nice antibody!The Calgranulin B Antibody (B-5): sc-376772 works well for IHC with formalin fixed, paraffin-embedded tissue sections, showing cytoplasmic and nuclear staining pattern.
Date published: 2017-01-19
Rated 5 out of 5 by CJ from Produced superb immunoperoxidase cytoplasmicProduced superb immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human oral mucosa tissue. -SCBT QC
Date published: 2015-04-09
Rated 5 out of 5 by TS from Produced positive Western Blot data of CalgranulinProduced positive Western Blot data of Calgranulin B expression in DMSO treated HL-60 and human PBL whole cell lysates. -SCBT QC
Date published: 2013-12-31
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Calgranulin B 抗体 (B-5) is rated 4.4 out of 5 by 7.
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