Date published: 2026-10-24
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Calgranulin A/B Antibody (27E10) - Flow Cytometry - Image 11454
Calgranulin A/B 抗体 (27E10) PE: sc-33714 PE. 固定和通透的人外周血白细胞的胞内 FCM 分析. 黑线直方图代表同型对照, 正常小鼠 IgG1: sc-2866.
Calgranulin A/B Antibody (27E10) - Flow Cytometry - Image 11454
Calgranulin A/B 抗体 (27E10) PE: sc-33714 PE. 固定和通透的人外周血白细胞的胞内 FCM 分析. 黑线直方图代表同型对照, 正常小鼠 IgG1: sc-2866.
Calgranulin A/B Antibody (27E10) - Immunohistochemistry - Image 293595
Calgranulin A/B 抗体 (27E10): sc-33714. 福尔马林固定, 石蜡包埋的人骨髓组织的免疫过氧化物酶染色显示造血细胞的胞浆和膜染色.
Calgranulin A/B Antibody (27E10) - Western Blotting - Image 411814
钙谷氨酰胺A/B抗体（27E10）：sc-33714。未经处理（A）和化学处理（B、C、D）的SP2/0全细胞裂解液中钙谷氨酰胺A/B表达的Western印迹分析。β-Actin (C4) sc-47778 用作加载对照。所用检测试剂：m-IgG Fc BP-HRP: sc-525409。
Calgranulin A/B 抗体 (27E10) PE: sc-33714 PE. 固定和通透的人外周血白细胞的胞内 FCM 分析. 黑线直方图代表同型对照, 正常小鼠 IgG1: sc-2866.

Calgranulin A/B 抗体 (27E10): sc-33714

4.4(5)
寫評論提問
说明书
  • Calgranulin A/B 抗体 27E10 是小鼠单克隆 IgG1 κ，Calgranulin A/B抗体, 在4篇文献中引用，规格为200 µg/ml
  • 针对human单核细胞
  • 推荐用于 human 来源的Calgranulin A/B WB, IP, IF, IHC(P) 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 Calgranulin A (C-10): sc-48352，可查看有标记的 Calgranulin A/B 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是Calgranulin A/B Antibody (27E10) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与Calgranulin A/B Antibody (27E10) 打包提供（请参阅下面的订购信息）。
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研究信息

関連項目

额外Calgranulin抗体，包括Calgranulin A, Calgranulin B和Calgranulin C

钙粘蛋白A/B抗体（27E10）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过免疫荧光（IF）、石蜡包埋切片免疫组织化学（IHCP）和流式细胞术（FCM）检测人源钙粘蛋白A/B蛋白。抗钙粒蛋白A/B抗体（27E10）有非结合型和多种结合型，包括藻红蛋白（PE）和异硫氰酸荧光素（FITC），可满足不同实验需求。钙调蛋白A/B（Calgranulin A/B）也称为S100A8/S100A9，在免疫反应中发挥着关键作用，特别是在炎症调节和免疫细胞向损伤或感染部位募集方面。S100A8/S100A9主要在巨噬细胞和中性粒细胞等骨髓细胞中表达，并参与异二聚体的形成，从而调节细胞增殖和凋亡等多种细胞过程。S100A8/S100A9在炎症反应中的存在使其成为囊性纤维化和类风湿性关节炎等疾病的重要生物标志物，凸显了S100A8/S100A9在诊断和治疗中的重要性。钙调蛋白A/B单克隆抗体（27E10）使研究人员能够深入了解炎症和免疫调节的机制，从而加深我们对各种病理的认识。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Calgranulin A/B 抗体 (27E10) 参考文献:

  1. 银屑病素（S100A7）和钙粘蛋白-B（S100A9）的诱导取决于活性氧，并且可通过Bcl-2和抗氧化剂下调。  |  Carlsson, H., et al. 2005. Cancer Biol Ther. 4: 998-1005. PMID: 16082188
  2. 巴雷特食管的高度不典型增生与钙粒蛋白A和B的表达增加有关。  |  Bax, DA., et al. 2007. Scand J Gastroenterol. 42: 902-10. PMID: 17613918
  3. 钙粒蛋白B（S100A9）与胰岛素抵抗和2型糖尿病的关联。  |  Ortega, FJ., et al. 2013. J Mol Med (Berl). 91: 523-34. PMID: 23207880
  4. 卵巢囊肿液是肿瘤生物标记物的缓存，其中包括钙调素 A 和钙调素 B 同工酶。  |  Skaggs, HS., et al. 2013. Cancer Invest. 31: 433-53. PMID: 23915068
  5. 急性吸入内毒素后钙粒蛋白A/B异二聚体的表达：蛋白质组学方法和验证。  |  Michel, O., et al. 2013. BMC Pulm Med. 13: 65. PMID: 24237763
  6. 转移素（S100A4）、钙粒蛋白A（S100A8）和钙粒蛋白B（S100A9）在口腔病变中的细胞分布和基因表达模式作为分子病理学的标记物。  |  Reckenbeil, J., et al. 2016. Cancer Invest. 34: 246-54. PMID: 27294692
  7. 胃肠道癌细胞中钙粘蛋白B相互作用蛋白的鉴定和网络分析。  |  Kim, KH., et al. 2017. PLoS One. 12: e0171232. PMID: 28152021
  8. 钙粒蛋白A（S100A8）免疫染色：非肌肉浸润性膀胱癌（NMIBC）患者风险评估的未来候选指标。  |  Nicklas, AP., et al. 2018. Adv Ther. 35: 2054-2068. PMID: 30232708
  9. IPF和NSIP患者支气管肺泡灌洗液中的钙粘蛋白B和KL-6。  |  Bennett, D., et al. 2019. Inflammation. 42: 463-470. PMID: 30680696
  10. 计算抑制S100A8（钙粒蛋白A）作为类风湿性关节炎的潜在非侵入性生物标志物。  |  Choudhury, K., et al. 2024. In Silico Pharmacol. 12: 25. PMID: 38590725

订购信息

产品名称产品编号规格价格数量收藏夹

Calgranulin A/B 抗体 (27E10)

sc-33714
200 µg/ml
$322.00

Calgranulin A/B (27E10): m-IgG Fc BP-HRP 套装

sc-536782
200 µg Ab; 10 µg BP
$361.00

Calgranulin A/B (27E10): m-IgGκ BP-HRP 套装

sc-533946
200 µg Ab; 40 µg BP
$361.00

Calgranulin A/B (27E10): m-IgG1 BP-HRP 套装

sc-544817
200 µg Ab; 20 µg BP
$361.00

Calgranulin A/B 抗体 (27E10) FITC

sc-33714 FITC
200 µg/ml
$336.00

Calgranulin A/B 抗体 (27E10) PE

sc-33714 PE
200 µg/ml
$349.00

Can Calgranulin A/B (27E10): sc-33714 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: DefinitelyNotMatt
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Calgranulin A/B (27E10): sc-33714 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24

How did you determine that the antibody is binding Calgranulin A/B? Do you know the epitope? Does it bind A or B ? i.e. do you know if it is binding the S100A8, S100A9 or S100A12 subunits ? Thanks!

Asked by: Mark R
Thank you for your inquiry. Our Calgranulin A/B antibody sc-33714 was raised against human monocytes, but the epitope has not been mapped. One publication, PubMedID 1529531, describes an intracellular epitope. This is a commercially available clone that has been determined to be Calgranulin A/B reactive. We do not have information specific to the reactivity with S100A8, S100A9 or S100A12 subunits.
Answered by: Technical Service
Date published: 2017-05-12
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Rated 5 out of 5 by fatulous from excellentit performs well in IHC exeriment ,we got the positive result
Date published: 2017-10-31
Rated 5 out of 5 by AbPolly from Available directly conjugatedThe PE conjugate of this antibody works very well for staining Calgranulin A/B in Flow Cytometry.
Date published: 2017-02-07
Rated 4 out of 5 by SF from Published WB data with human carcinomaPublished WB data with human carcinoma - SCBT Publication Review
Date published: 2015-02-16
Rated 4 out of 5 by JM from Produced robust immunoperoxidase cytoplasmicProduced robust immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human bone marrow tissue. -SCBT QC
Date published: 2015-01-12
Rated 4 out of 5 by LR from Produced good intracellular FCM data forProduced good intracellular FCM data for fixed and permeabilized human peripheral blood leukocytes. -SCBT QC
Date published: 2013-12-26
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Calgranulin A/B 抗体 (27E10) is rated 4.4 out of 5 by 5.
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