Date published: 2025-9-6

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BSPII 抗体 (ID1.2): sc-73497

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说明书
  • BSPII 抗体 ID1.2 是小鼠单克隆 IgG1, 在5篇文献中引用,提供 100 µg/ml
  • 针对human来源的骨组织分离的骨唾液蛋白
  • 推荐用于 human 来源的recombinant and native BSPII WB, IF 和 IHC(P)检测; 不会与 human Osteonectin or human Osteopontin产生交联反应
  • 目前,我们还没有完成BSPII 抗体 (ID1.2)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

BSPII抗体(ID1.2)是一种小鼠单克隆IgG1抗体,可通过蛋白质印迹(WB)、免疫荧光(IF)和石蜡包埋切片免疫组织化学(IHCP)等方法检测人体样本中的BSPII。BSPII,也称为骨唾液蛋白II或整合素结合唾液蛋白,是一种由成骨细胞、骨细胞、破骨细胞、肥厚软骨细胞和其他骨骼相关细胞类型合成的分泌酸性糖基化、硫酸化和磷酸化蛋白。作为骨基质的主要结构成分,BSPII约占人体骨骼中非胶原蛋白的12%,对调节骨骼矿化至关重要。BSPII在最初的矿化过程中起着重要作用,通过成核羟基磷灰石晶体的形成,从而促进骨骼、牙骨质和牙本质的发育。此外,BSPII属于蛋白质的同源家族,具有RGD序列,可与维蛋白受体整合素αV相互作用,促进细胞附着和信号传导。值得注意的是,BSPII在多种癌症中也有表达,包括肺癌、甲状腺癌、乳腺癌和前列腺癌,这凸显了BSPII作为肿瘤进展生物标志物和治疗干预靶标的潜力。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

BSPII 抗体 (ID1.2)

sc-73497
100 µg/ml
$316.00

Can I use sc-73497 for frozen sections (cryosections) from mouse bone which are tagged with Ibsp-GFP ?

Asked by: theqatron
Thank you for your question. BSPII Antibody (ID1.2): sc-73497 is recommended for detection of recombinant and native BSPII of human origin by WB, IF (including immunohistochemistry on cryosections) and IHC(P). This antibody is however not recommended for the detection of the protein of mouse origin. For additional information, please contact our Technical Service at europe@scbt.com
Answered by: Tech Support Europe
Date published: 2020-06-15

Can sc-43497 BSPII antibody can be used for cryosectioned bone (femur or vertebra) samples?

Asked by: dilara
Thank you for your question. BSPII Antibody (ID1.2): sc-73497 is recommended for detection of recombinant and native BSPII of human origin by WB, IF and IHC(P). If your samples are from human tissues this antibody will detect BSPII in those samples. You might also want to check out our recommended protocol by following this link: https://www.scbt.com/resources/protocols/immunoperoxidase-staining
Answered by: Tech Support Europe
Date published: 2020-06-15

Can sc-73497: BSPII (ID1.2) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Dr Ninau Qelp
Thank you for your question. Yes, sc-73497: BSPII (ID1.2) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 4 out of 5 by from This antibody was used in a publication forThis antibody was used in a publication for IHC on human MSCs - SCBT Publication Review
Date published: 2013-06-10
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BSPII 抗体 (ID1.2) is rated 4.0 out of 5 by 1.
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