BPPA MF: C30H36N4O4*2CH3COOH
MW: 637.00
A potent, novel and selective inhibitor of human telomerase.

BPPA

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同义词: 2,6-bis(3-Piperidinopropionamido)anthraquinone diacetate
应用; A potent, novel and selective inhibitor of human telomerase
纯度: 97%
分子量: 637.00
分子式: C30H36N4O4*2CH3COOH
* 参考分析证明 大量特定数据 (包括水 含量).
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BPPA is a potent, novel and selective inhibitor of human telomerase that has displayed strong cytotoxic activity against human carcinoma cell lines through a mechanism of action unrelated to telomerase inhibition.


参考文献

1. Perry, P.J., et al. 1998. J. Med. Chem. 41: 3253-3260. PMID: 9703471

物理状态 :
Solid
溶解度 :
Soluble in water (110 mg/ml), DMSO (20 mg/ml), and ethanol (2 mg/ml).
保存 :
Store at -20° C
IC50 :
Telomerase : IC50 = 4.5 µM (human); Inhibit SKOV-3-cell growth: IC50 = 2.1 µM; Inhibit CH1-cell growth: IC50 = 14.5 µM; Inhibit A2780-cell growth: IC50 = 2.45 µM
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
374316
SMILES :
CC(=O)O.C1CCN(C(C1)CO)CCC(=O)NC2=CC3=C(C=C2)C(=O)C4=C(C3=O)C=CC(=C4)NC(=O)CCN5CCCCC5CO

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