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Benzethonium hydroxide solution (CAS 498-77-1)

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Application:
Benzethonium hydroxide solution is a solution used in scintillation experiments
CAS Number:
498-77-1
Molecular Weight:
429.64
Molecular Formula:
C27H43NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzethonium hydroxide solution is an aqueous solution of a quaternary ammonium compound that exhibits strong surfactant and antimicrobial properties. Its mode of action involves the disruption of microbial cell membranes. As a surfactant, it can interact with the lipid bilayer of the cell membrane, compromising its integrity. This disruption leads to increased membrane permeability, causing the leakage of intracellular components, ultimately resulting in cell death. The compound′s ability to bind and alter membrane permeability makes it particularly effective against a broad spectrum of bacteria, fungi, and enveloped viruses. This capability is further enhanced by its stability and solubility in aqueous solutions, facilitating its widespread use in formulations where potent antimicrobial action is desired.


Benzethonium hydroxide solution (CAS 498-77-1) References

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  3. Arginase expression and modulation of IL-1beta-induced nitric oxide generation in rat and human islets of Langerhans.  |  Stickings, P., et al. 2002. Nitric Oxide. 7: 289-96. PMID: 12446178
  4. Organic carbon utilization by obligately and facultatively autotrophic beggiatoa strains in homogeneous and gradient cultures.  |  Hagen, KD. and Nelson, DC. 1996. Appl Environ Microbiol. 62: 947-53. PMID: 16535281
  5. Ornithine decarboxylase activity in tissues from rats exposed to 60 Hz magnetic fields, including harmonic and transient field characteristics.  |  McDonald, LJ., et al. 2003. Toxicol Mech Methods. 13: 31-8. PMID: 20021180
  6. Topically applied L-carnitine effectively reduces sebum secretion in human skin.  |  Peirano, RI., et al. 2012. J Cosmet Dermatol. 11: 30-6. PMID: 22360332
  7. Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells.  |  Li, J., et al. 2016. Amino Acids. 48: 1003-1012. PMID: 26704566
  8. Synthesis and Deployment of an Elusive Fluorovinyl Cation Equivalent: Access to Quaternary α-(1'-Fluoro)vinyl Amino Acids as Potential PLP Enzyme Inactivators.  |  McCune, CD., et al. 2017. J Am Chem Soc. 139: 14077-14089. PMID: 28906111
  9. A Modified Tripeptide Motif of RS1 (RSC1A1) Down-Regulates Exocytotic Pathways of Human Na+-d-glucose Cotransporters SGLT1, SGLT2, and Glucose Sensor SGLT3 in the Presence of Glucose.  |  Schäfer, N., et al. 2019. Mol Pharmacol. 95: 82-96. PMID: 30355744
  10. BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.  |  Yoneshiro, T., et al. 2019. Nature. 572: 614-619. PMID: 31435015
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  12. Kruppel-like factor 15 regulates fuel switching between glucose and fatty acids in brown adipocytes.  |  Nabatame, Y., et al. 2021. J Diabetes Investig. 12: 1144-1151. PMID: 33480176
  13. Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity.  |  Yoshida, N., et al. 2021. iScience. 24: 103342. PMID: 34805797

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzethonium hydroxide solution, 25 ml

sc-280610
25 ml
$155.00

Benzethonium hydroxide solution, 100 ml

sc-280610A
100 ml
$468.00

Benzethonium hydroxide solution, 500 ml

sc-280610B
500 ml
$1083.00

Benzethonium hydroxide solution, 1 L

sc-280610C
1 L
$1851.00