Date published: 2025-9-7

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BAFF-R 抗体 (H-1): sc-365410

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说明书
  • BAFF-R 抗体 H-1 是小鼠单克隆 IgG2b κ,BAFF-R抗体, 在2篇文献中引用,规格为200 µg/ml
  • 免疫human物种的BAFF-R的氨基酸22-184
  • BAFF-R 抗体 (H-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 BAFF-R
  • 抗BAFF-R抗体(H-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取BAFF-R (H-1): sc-365410免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG2b BP-HRPm-IgGκ BP-HRP 是 BAFF-R 抗体 (H-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与BAFF-R 抗体 (H-1) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

BAFF-R抗体(H-1)是一种IgG2b κ型小鼠单克隆BAFF-R抗体(也称为BAFF-R抗体),能够通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组化(IHC,石蜡切片)和酶联免疫吸附测定(ELISA)等方法检测小鼠、大鼠和人类来源的BAFF-R蛋白。BAFF-R抗体(H-1)既可以作为非共轭形式的抗BAFF-R抗体提供,也可以作为多种共轭形式的抗BAFF-R抗体提供,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®共轭物。TNF细胞因子家族成员TALL-1(也被称为BAFF、zTNF4、THANK和BLYS)是一种II型膜蛋白,具有与其他肿瘤坏死因子(TNF)细胞因子家族成员相似的特征。TALL-1能够与三种受体TACI、BCMA和BAFF-R结合,但与其他TNF受体不同的是,BAFF-R只特异性地结合TALL-1配体。编码人类BAFF-R的基因位于染色体22q13.1-q13.31,在脾脏和淋巴结中高表达,而在外周血白细胞和胸腺中表达水平较低。BAFF-R的表达对于将过渡性B细胞选择进入成熟B细胞池至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

BAFF-R 抗体 (H-1) 参考文献:

  1. 新型细胞因子 THANK 的鉴定和特征描述:THANK 是 TNF 的同源物,可激活细胞凋亡, 核因子-kappaB 和 c-Jun NH2 端激酶。  |  Mukhopadhyay, A., et al. 1999. J Biol Chem. 274: 15978-81. PMID: 10347144
  2. BAFF是肿瘤坏死因子家族的一种新型配体,可刺激B细胞生长。  |  Schneider, P., et al. 1999. J Exp Med. 189: 1747-56. PMID: 10359578
  3. BLyS:肿瘤坏死因子家族成员,B 淋巴细胞刺激物。  |  Moore, PA., et al. 1999. Science. 285: 260-3. PMID: 10398604
  4. BAFF-R 是一种新发现的 TNF 受体,能与 BAFF 发生特异性相互作用。  |  Thompson, JS., et al. 2001. Science. 293: 2108-11. PMID: 11509692
  5. 免疫学成熟B细胞万岁--一个令人费解的谜团终于解开了。  |  Waldschmidt, TJ. and Noelle, RJ. 2001. Science. 293: 2012-3. PMID: 11557866
  6. BAFF受体缺陷小鼠的中枢神经系统自身免疫加速  |  Kim, SS., et al. 2011. J Neurol Sci. 306: 9-15. PMID: 21529843
  7. BAFF 受体缺乏可减少小鼠动脉粥样硬化的发生--简要报告。  |  Sage, AP., et al. 2012. Arterioscler Thromb Vasc Biol. 32: 1573-6. PMID: 22426131
  8. BAFF 受体 TACI 可控制调节性 B 细胞和 CLL B 细胞产生 IL-10。  |  Saulep-Easton, D., et al. 2016. Leukemia. 30: 163-72. PMID: 26139429
  9. 早期阻断 BAFF 受体可减轻小鼠的 Sjögren 综合征:同时靶向 CXCL13 和 BAFF 受体可预防唾液功能减退。  |  Sharma, A., et al. 2016. Clin Immunol. 164: 85-94. PMID: 26826598
  10. BAFF 可上调 CD28/B7 和 CD40/CD154 的表达,并通过 BAFF 受体促进体外小鼠 T 细胞和 B 细胞的相互作用。  |  Zhang, F., et al. 2016. Acta Pharmacol Sin. 37: 1101-9. PMID: 27180986
  11. 阻断 T 细胞上的 BAFF 受体 BR3 可增强其活化和细胞毒性。  |  Bloom, DD., et al. 2018. J Immunother. 41: 213-223. PMID: 29309290
  12. 单核细胞上 BAFF 受体 BR3 的高表达与 B 细胞活化和原发性斯约格伦综合征患者的临床特征相关。  |  Yoshimoto, K., et al. 2020. Arthritis Res Ther. 22: 157. PMID: 32576236

订购信息

产品名称产品编号规格价格数量收藏夹

BAFF-R 抗体 (H-1)

sc-365410
200 µg/ml
$316.00

BAFF-R (H-1): m-IgGκ BP-HRP 套装

sc-522238
200 µg Ab, 40 µg BP
$354.00

BAFF-R (H-1): m-IgG2b BP-HRP 套装

sc-549016
200 µg Ab; 10 µg BP
$354.00

BAFF-R 抗体 (H-1) AC

sc-365410 AC
500 µg/ml, 25% agarose
$416.00

BAFF-R 抗体 (H-1) HRP

sc-365410 HRP
200 µg/ml
$316.00

BAFF-R 抗体 (H-1) FITC

sc-365410 FITC
200 µg/ml
$330.00

BAFF-R 抗体 (H-1) PE

sc-365410 PE
200 µg/ml
$343.00

BAFF-R 抗体 (H-1) Alexa Fluor® 488

sc-365410 AF488
200 µg/ml
$357.00

BAFF-R 抗体 (H-1) Alexa Fluor® 546

sc-365410 AF546
200 µg/ml
$357.00

BAFF-R 抗体 (H-1) Alexa Fluor® 594

sc-365410 AF594
200 µg/ml
$357.00

BAFF-R 抗体 (H-1) Alexa Fluor® 647

sc-365410 AF647
200 µg/ml
$357.00

BAFF-R 抗体 (H-1) Alexa Fluor® 680

sc-365410 AF680
200 µg/ml
$357.00

BAFF-R 抗体 (H-1) Alexa Fluor® 790

sc-365410 AF790
200 µg/ml
$357.00

I need to use an antibody to detect the protein in samples of equine origin. Do you know if sc-365410: BAFF-R (H-1) mouse monoclonal antibody will work?

Asked by: Germaine
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 2 out of 5 by from Rat and Cat tissue IHCIt was an antibody that I acquired as a test sample. the antibody did not work in ihc on Rat and Cat FFPE tissues. IHC technique details: Spleen 1/50 dilution BAFF-R 18 hours +4C incubation. Sitrate pH 6.0 HiER
Date published: 2022-04-13
Rated 5 out of 5 by from Great Antibody in WB DetectionThe antibody worked well for WB detection at 1:200 in splenocyte lysis.
Date published: 2017-08-21
Rated 4 out of 5 by from BAFF-R+ cells in ducksWe detected BAFF-R+ cells (green signal in the pictures; presumably B-cells) by IF in cryo-sections of nasal mucosa of ducks infected by the neuropathogenic schistosome Trichobilharzia regenti. Furthermore, the BAFF-R+ cells were also seen in a spleen of the duck.
Date published: 2017-03-07
Rated 5 out of 5 by from Great Western Blot data of BAFFGreat Western Blot data of BAFF-R expression in non-transfected and human BAFF-R transfected 293 whole cell lysates. -SCBT QC
Date published: 2015-03-30
Rated 5 out of 5 by from Great Western Blot data of BAFFGreat Western Blot data of BAFF-R expression in IB4, BJAB and Raji whole cell lysates. -SCBT QC
Date published: 2013-10-11
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BAFF-R 抗体 (H-1) is rated 4.2 out of 5 by 5.
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