Atazanavir sulfate CAS: 229975-97-7
MF: C38H52N6O7•H2SO4
MW: 802.93
A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.

Atazanavir sulfate (CAS 229975-97-7)

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同义词: BMS-232632-05, Reyataz
应用; A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor
CAS号码: 229975-97-7
纯度: ≥98%
分子量: 802.93
分子式: C38H52N6O7•H2SO4
* 参考分析证明 大量特定数据 (包括水 含量).
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Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC50 of approximately 47 nM. Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations.

物理状态 :
Solid
溶解度 :
Soluble in water (4-5 mg/ml), and methanol.
保存 :
Store at 4° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
158550
MDL 号码 :
MFCD08067748
SMILES :
CC(C)(C)[[email protected]@H](C(=O)N[[email protected]@H](CC1=CC=CC=C1)[[email protected]](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[[email protected]](C(C)(C)C)NC(=O)OC)O)NC(=O)OC.OS(=O)(=O)O

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