Molecular structure of Aroclor 1254, CAS Number: 11097-69-1
Aroclor 1254 (CAS 11097-69-1)
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Alternate Names:
2,2′,3,3′,4-pentachlorobiphenyl
Application:
Aroclor 1254 is a mixture of different substituted polychlorobiphenyls
CAS Number:
11097-69-1
Molecular Weight:
326.43
Molecular Formula:
C12H5Cl5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Aroclor 1254 is a mixture of different substituted polychlorobiphenyls. Aroclor 1254 is believed to function as an endocrine disruptor, capable of interfering with the regular operation of the endocrine system. Additionally, it is believed to function as an immunotoxicant, capable of interfering with the normal functioning of the immune system. Aroclor 1254 is also believed to be a carcinogen, capable of causing cancer in humans.
Aroclor 1254 (CAS 11097-69-1) References
- Aroclor 1254 induced cytotoxicity and mitochondrial dysfunction in isolated rat hepatocytes. | Aly, HA. and Domènech, O. 2009. Toxicology. 262: 175-83. PMID: 19486918
- Aroclor 1254 induced oxidative stress and mitochondria mediated apoptosis in adult rat sperm in vitro. | Aly, HAA. 2013. Environ Toxicol Pharmacol. 36: 274-283. PMID: 23686007
- Effects of Aroclor 1254 on in vivo oocyte maturation in the mouse. | Liu, S., et al. 2014. PLoS One. 9: e102064. PMID: 25013911
- Aroclor 1254-induced genotoxicity in male gonads through oxidatively damaged DNA and inhibition of DNA repair gene expression. | Attia, SM., et al. 2014. Mutagenesis. 29: 379-84. PMID: 25113976
- Aroclor 1254 causes atrophy of exocrine pancreas in mice and the mechanism involved. | Lin, M., et al. 2016. Environ Toxicol. 31: 671-8. PMID: 25409620
- Aroclor 1254 inhibits cell viability and induces apoptosis of human A549 lung cancer cells by modulating the intracellular Ca(2+) level and ROS production through the mitochondrial pathway. | Zhong, Y., et al. 2015. J Environ Sci Health A Tox Hazard Subst Environ Eng. 50: 806-13. PMID: 26030686
- Exposure to Aroclor-1254 impairs spindle assembly during mouse oocyte maturation. | Liu, SZ., et al. 2016. Environ Toxicol. 31: 1652-1662. PMID: 26174069
- Aroclor 1254 inhibits vasotocinergic pathways related to osmoregulatory and stress functions in the gilthead sea bream (Sparus aurata, Linnaeus 1758). | Skrzynska, AK., et al. 2019. Aquat Toxicol. 212: 98-109. PMID: 31082703
- Exposure to Aroclor 1254 differentially affects the survival of pancreatic β-cells and α-cells in the male mice and the potential reason. | Fang, L., et al. 2020. Ecotoxicol Environ Saf. 188: 109875. PMID: 31706244
- Dynamic transcriptome response in Meretrix meretrix to Aroclor 1254 exposure. | Li, Y., et al. 2021. Ecotoxicol Environ Saf. 207: 111485. PMID: 33254386
- Lycopene ameliorates the effect of Aroclor 1254 on morphology, proliferation, and angiogenesis of the thyroid gland in rat. | Ibrahim, MAA., et al. 2021. Toxicology. 452: 152722. PMID: 33592256
- Aroclor 1254 impairs sperm quality, fertilization ability, and embryo development of rainbow trout (Oncorhynchus mykiss). | Kocabaş, M., et al. 2022. Environ Sci Pollut Res Int. 29: 84581-84589. PMID: 35781661
- The effects of Aroclor 1254 alone and in combination with X-rays on the male mice germ cells quantity and quality. | Dobrzyńska, MM. and Radzikowska, J. 2022. Toxicology. 477: 153273. PMID: 35872225
- Aroclor 1254 induced inhibitory effects on osteoblast differentiation in murine MC3T3-E1 cells through oxidative stress. | Chen, Y., et al. 2022. Front Endocrinol (Lausanne). 13: 940624. PMID: 36353240
Inhibitor of:
PCB.Activator of:
CAR, CYP2B13, CYP2B19, CYP2B23, CYP4A14, CYP4F2, SULT1A3, SULT1A4, and VACVase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aroclor 1254, 50 mg | sc-257096 | 50 mg | $143.00 |