Date published: 2025-9-5

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NUAK1/ARK5 抗体 (H-12): sc-393459

5.0(1)
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说明书
  • NUAK1/ARK5抗体(H-12)是小鼠单克隆IgG3 (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的ARK5的N-terminus附近的氨基酸48-69之间
  • 推荐用于 human 来源的NUAK1 WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG3 BP-HRP 是NUAK1/ARK5 抗体 (H-12) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与NUAK1/ARK5 抗体 (H-12) 组合成套装提供。 (请参阅下面的订购信息)。

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    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    NUAK1/ARK5 抗体 (H-12) 参考文献:

    1. 终止子轴突分支受 LKB1-NUAK1 激酶通路通过突触前线粒体捕获调节。  |  Courchet, J., et al. 2013. Cell. 153: 1510-25. PMID: 23791179
    2. microRNA-203 通过靶向 NUAK1 抑制头颈癌的侵袭和上皮-间质转化诱导。  |  Obayashi, M., et al. 2016. Oncotarget. 7: 8223-39. PMID: 26882562
    3. 减少 Nuak1 会降低 Tau,并逆转 Tauopathy 小鼠模型的表型。  |  Lasagna-Reeves, CA., et al. 2016. Neuron. 92: 407-418. PMID: 27720485
    4. NUAK1 对蛋白磷酸酶 1 的局部抑制促进了剪接体的活性,并揭示了 MYC 对转录的反馈控制。  |  Cossa, G., et al. 2020. Mol Cell. 77: 1322-1339.e11. PMID: 32006464
    5. NUAK1 通过调节球体内纤维粘连蛋白的产生,在促进卵巢癌转移方面发挥了新的作用。  |  Fritz, JL., et al. 2020. Cancers (Basel). 12: PMID: 32429240
    6. 使用多靶点抑制剂 MRT68921 双重靶向 NUAK1 和 ULK1 可发挥强大的抗肿瘤活性。  |  Chen, Y., et al. 2020. Cell Death Dis. 11: 712. PMID: 32873786
    7. 沉默 NUAK1 和 -2 以及假定的 NUAK 抑制剂 HTH01-015 和 WZ4003 可抑制人前列腺基质细胞的生长和收缩。  |  Liu, Y., et al. 2023. Front Pharmacol. 14: 1105427. PMID: 37188272
    8. LncRNA HOTAIR通过表观遗传抑制miR-145-5p的表达调控NUAK1,从而增强上皮细胞向间质转化,促进肝癌的迁移和侵袭  |  Chu, DX., et al. 2023. J Cancer. 14: 2329-2343. PMID: 37576402
    9. NUAK1的预后意义及其与胃腺癌免疫浸润的关系  |  Ni, X., et al. 2024. Discov Oncol. 15: 800. PMID: 39692916
    10. 靶向甲羟戊酸途径可增强NUAK1抑制诱导的免疫原性细胞死亡和抗肿瘤免疫。  |  Gui, L., et al. 2025. Cell Rep Med. 6: 101913. PMID: 39824180

    订购信息

    产品名称产品编号规格价格数量收藏夹

    NUAK1/ARK5 抗体 (H-12)

    sc-393459
    200 µg/ml
    $316.00

    NUAK1/ARK5 (H-12): m-IgG3 BP-HRP 套装

    sc-550491
    200 µg Ab; 40 µg BP
    $354.00

    NUAK1/ARK5 (H-12) 中和勝肽

    sc-393459 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-393459 P appropriate for?

    Asked by: jerojero
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Good Western blot data of ARK5 expression in nonGood Western blot data of ARK5 expression in non-transfected and human ARK5 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-04-02
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    NUAK1/ARK5 抗体 (H-12) is rated 5.0 out of 5 by 1.
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