8-Hydroxyquinoline CAS: 148-24-3
MF: C9H7NO
MW: 145.17
A monoprotic bidentate chelating agent and dye.

8-Hydroxyquinoline (CAS 148-24-3)

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同义词: Oxine; 8-Quinolinol; 8-Oxychinolin
应用; A monoprotic bidentate chelating agent and dye
CAS号码: 148-24-3
纯度: ≥99%
分子量: 145.17
分子式: C9H7NO
* 参考分析证明 大量特定数据 (包括水 含量).
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8-Hydroxyquinoline is a monoprotic bidentate chelating agent The reaction of 8-hydroxyquinoline with aluminium(III) results in Alq3, a common component of organic light-emitting diodes (OLED's). Variations in the substituents on the quinoline rings affect its luminescent properties. 8-Hydroxyquinoline is employed in precipitating and separating metals, the preparation of fungicides, and as a dye.


参考文献

1. Montes, V.A., er al. 2006. Chemistry. 12: 4523-4535. PMID: 16619313
2. Katakura, R., et al. 2006. Inorg Chem. 45: 5730-5732. PMID: 16841973

外观 :
Powder
物理状态 :
Solid
溶解度 :
Soluble in acetone, ethanol, chloroform, and benzene. Insoluble in water.
保存 :
Store at room temperature
熔点 :
70-73° C (lit.)
沸点 :
267° C (lit.) at 752 mmHg
密度 :
1.03 g/cm3 at 20° C
折射率 :
n20D 1.69 (Predicted)
IC50 :
BChE: IC50 > 100 nM (human); AChE: IC50 > 100 nM (human); FM3A: IC50 = 2.1 µM (mouse); MetAP-2: IC50 = 5.6 µM (human); MetAP-1: IC50 = 21.5 µM (human).
Ki 数据 :
Thermolysin: Ki= 214 µM (bacillus thermoproteolyticus)
pK值 :
pKa: 5.06 (Predicted), pKb: 9.81 (Predicted)
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
3
RTECS :
VC4200000
PubChem CID :
1923
默克索引 :
14: 4843
MDL 号码 :
MFCD00006807
EC号码 :
205-711-1
Beilstein 注册 :
114512
SMILES :
C1=CC2=C(C(=C1)O)N=CC=C2

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引用1 - 11

PMID: # 31272829  Fang, MY.|Markmiller, S.|Vu, AQ.|Javaherian, A.|Dowdle, WE.|Jolivet, P.|Bushway, PJ.|Castello, NA.|Baral, A.|Chan, MY.|Linsley, JW.|Linsley, D.|Mercola, M.|Finkbeiner, S.|Lecuyer, E.|Lewcock, JW.|Yeo, GW.| et al. 2019. Neuron.

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