Molecular structure of 5-trans Fluprostenol isopropyl ester
5-trans Fluprostenol isopropyl ester
Application:
5-trans Fluprostenol isopropyl ester is an impurity of luprostenol isopropyl ester perperations
Molecular Weight:
500.6
Molecular Formula:
C26H35F3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Travoprost is the Alcon trade name for fluprostenol isopropyl ester, which is an F-series prostaglandin analog that has been approved for use as an ocular hypotensive drug(1,2). Fluprostenol isopropyl ester is a prodrug that is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid(1). 5-trans Fluprostenol isopropyl ester (5-trans Travoprost) is an impurity that is routinely found in bulk preparations of fluprostenol isopropyl ester in amounts ranging from 1-3%. The pharmacology of 5-trans fluprostenol isopropyl ester has not been studied extensively to date.
5-trans Fluprostenol isopropyl ester References
- Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. | Hellberg, MR., et al. 2001. J Ocul Pharmacol Ther. 17: 421-32. PMID: 11765147
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5-trans Fluprostenol isopropyl ester, 1 mg | sc-223703 | 1 mg | $84.00 | |||
5-trans Fluprostenol isopropyl ester, 5 mg | sc-223703A | 5 mg | $379.00 |