Date published: 2026-5-9

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5-Chloro-1,2-benzisothiazol-3(2H)-one (CAS 4337-43-3)

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Alternate Names:
5-Chloro-1,2-benzisothiazol-3(2H)-one; 5-Chlorobenzisothiazolone
CAS Number:
4337-43-3
Molecular Weight:
185.63
Molecular Formula:
C7H4ClNOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The compound 5-Chloro-1,2-benzisothiazol-3(2H)-one finds extensive application as a biocide and preservative across various industries. Its primary role involves controlling the proliferation of bacteria and fungi, while also safeguarding against product spoilage..Its mode of action revolves around the disruption of microbial cell membranes. By binding to and forming complexes with these membranes, 5-Chloro-1,2-benzisothiazol-3(2H)-one obstructs their integrity, thereby curtailing microorganism growth. 5-Chloro-1,2-benzisothiazol-3(2H)-one exhibits the capability to hinder nutrient and molecule uptake through its interactions with cell membranes, contributing to its antimicrobial effects.


5-Chloro-1,2-benzisothiazol-3(2H)-one (CAS 4337-43-3) References

  1. Lipophilicity of a series of 1,2-benzisothiazol-3(2H)-ones determined by reversed-phase thin-layer chromatography.  |  Sławik, T. and Kowalski, C. 2002. J Chromatogr A. 952: 295-9. PMID: 12064543

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-Chloro-1,2-benzisothiazol-3(2H)-one, 50 mg

sc-207018A
50 mg
$218.00

5-Chloro-1,2-benzisothiazol-3(2H)-one, 100 mg

sc-207018
100 mg
$302.00

5-Chloro-1,2-benzisothiazol-3(2H)-one, 250 mg

sc-207018B
250 mg
$666.00

5-Chloro-1,2-benzisothiazol-3(2H)-one, 500 mg

sc-207018C
500 mg
$1217.00

5-Chloro-1,2-benzisothiazol-3(2H)-one, 1 g

sc-207018D
1 g
$2081.00