3-Deazaneplanocin, HCl salt CAS: 120964-45-6
MF: C12H14N4O3•HCl
MW: 298.72
An effective S-adenosylhomocysteine hydrolase inhibitor.

3-Deazaneplanocin, HCl salt (CAS 120964-45-6)

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同义词: (1s,2r,5r)-5-(4-amino-1h-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
应用; An effective S-adenosylhomocysteine hydrolase inhibitor
CAS号码: 120964-45-6
纯度: ≥97%
分子量: 298.72
分子式: C12H14N4O3•HCl
* 参考分析证明 大量特定数据 (包括水 含量).
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3-Deazaneplanocin, HCl salt is a carbocyclic analog of adenosine that acts as an effective SAHH (S-adenosylhomocysteine hydrolase) inhibitor. Research indicates that the compound may have antiviral properties and has been used in human promyelocytic leukemia cell line HL-60 studies. 3-Deazaneplanocin, HCl salt is an inhibitor of ENX-1.


参考文献

1. Glazer, R.I., et al. 1986. Biochem. Biophys. Res. Commun. 135: 688-694. PMID: 3457563

物理状态 :
Solid
溶解度 :
Soluble in PBS & cell culture medium (1 mg/ml), and water (≥25 mg/ml).
pH :
L
保存 :
Store at 4° C
折射率 :
n20D 1.82 (Predicted)
IC50 :
Vero: IC50 = 0.55 ug.mL-1 (chlorocebus aethiops)
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
3
PubChem CID :
14563109
MDL 号码 :
MFCD18782644
SMILES :
C1=CN=C(C2=C1N(C=N2)[[email protected]@H]3C=C([[email protected]]([[email protected]]3O)O)CO)N

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分析证明书

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PMID: # 25549357  Ferraro, A. et al. 2014. PloS one. 9: e115276.

PMID: # 23933322  Lee, JK. et al. 2013. Biochem. Biophys. Res. Commun. 438: 647-52.

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