The category of compounds identified as Vmn2r12 Inhibitors consists of chemicals that, while not directly targeting Vmn2r12, exert their influence on various signaling pathways and cellular processes that could, in turn, modulate the activity or expression of Vmn2r12. These compounds operate through diverse mechanisms, such as antagonism of specific receptors, inhibition of kinase activity, modulation of calcium signaling, and alteration of cytoskeletal dynamics. Through these mechanisms, they have the capacity to indirectly impact the signal transduction pathways and cellular contexts in which Vmn2r12 functions, thereby offering a strategic approach to studying and potentially modulating the activity of this protein.
The selection of these compounds reflects a nuanced understanding of cellular signaling as a highly interconnected network, where changes in one part of the system can have widespread effects on other components. By targeting various nodes within this network-such as GPCRs, kinases, and calcium signaling pathways-the listed chemicals can alter the cellular milieu and the flow of biochemical signals within the cell. This, in turn, can influence the activity of Vmn2r12, even in the absence of direct interaction with the protein. Such an approach underscores the complexity of cellular signaling and the potential for indirect strategies to elucidate the functions of specific proteins within this web of interactions. Through the modulation of signaling pathways that Vmn2r12 is either directly or indirectly involved in, these compounds provide valuable tools for probing the biological roles of Vmn2r12 and for exploring the intricate regulatory mechanisms that govern cellular response mechanisms.
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产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
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ZM 241385 | 139180-30-6 | sc-361421 sc-361421A | 5 mg 25 mg | $90.00 $349.00 | 1 | |
一种选择性腺苷 A2A 受体拮抗剂,可能会影响 Vmn2r12 可能参与的 GPCR 介导的信号通路。 | ||||||
Clozapine | 5786-21-0 | sc-200402 sc-200402A | 50 mg 500 mg | $68.00 $357.00 | 11 | |
氯氮平(Clozapine)是一种非典型抗精神病药物,可作为5-羟色胺拮抗剂。它对5-羟色胺受体的抑制会中断Vmn2r121参与的信号通路,从而抑制该蛋白的功能。 | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
一种广谱蛋白激酶 C (PKC) 抑制剂,可影响与 Vmn2r12 功能交叉的信号通路。 | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
抑制 ROCK(Rho 相关蛋白激酶),可能会影响与 Vmn2r12 信号相关的肌动蛋白细胞骨架动力学。 | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
抑制肌球蛋白轻链激酶(MLCK),可能会影响影响 Vmn2r12 信号传导的细胞过程。 | ||||||
Ritanserin | 87051-43-2 | sc-203681 sc-203681A | 10 mg 50 mg | $87.00 $306.00 | 2 | |
利坦色林(Ritanserin)是一种选择性5-羟色胺受体拮抗剂,可通过阻断与Vmn2r121相同的信号通路中的5-羟色胺受体来抑制Vmn2r121,从而抑制其活性。 | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
抑制 TGF-beta I 型受体 ALK5,可能会影响 Vmn2r12 参与的信号通路。 | ||||||
Ondansetron | 99614-02-5 | sc-201127 sc-201127A | 10 mg 50 mg | $80.00 $326.00 | 1 | |
Ondansetron是一种5-羟色胺5-HT3受体拮抗剂,用于预防恶心和呕吐。它可以通过阻断可能参与相同通路的5-羟色胺受体来抑制Vmn2r121,从而可能抑制Vmn2r121的功能。 | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
抑制 FGFR1 酪氨酸激酶,可能会调节与 Vmn2r12 活性交叉的信号通路。 | ||||||
Ketanserin | 74050-98-9 | sc-279249 | 1 g | $700.00 | ||
酮塞林是一种选择性血清素 5-HT2A 受体拮抗剂。通过抑制这些受体,它可以阻止 Vmn2r121 可能参与的信号级联的激活,从而抑制 Vmn2r121 的活性。 |