Date published: 2025-10-10

021-6093-6350

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TSPAN18激活剂

Tetraspanins, including TSPAN18, are integral membrane proteins characterized by their four transmembrane domains. These proteins are involved in a wide variety of cellular processes, including cell development, activation, growth, and motility, largely due to their ability to associate with other proteins and form complex networks known as tetraspanin-enriched microdomains (TEMs). These domains serve as platforms for signal transduction, influencing the activities of associated proteins. Therefore, any molecule that could interact with TSPAN18 or associated proteins in a way that promotes these activities might be considered a potential "TSPAN18 Activator".

It's crucial to note that these activators would likely need to be able to interact with the cellular membrane in order to influence the function of TSPAN18, given its location within the membrane. Activators could potentially function through direct interaction with TSPAN18 or through indirect mechanisms, such as modifying the activity of proteins associated with TSPAN18 or altering the lipid environment of the membrane to influence TSPAN18 function. It's also possible that these activators could function via intracellular mechanisms, potentially influencing the transcription or translation of TSPAN18. In all cases, the end result would be an upregulation of the normal function of TSPAN18, potentially leading to enhanced cell development, activation, growth, or motility.

関連項目

产品名称CAS #产品编号数量价格应用排名

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA 可激活蛋白激酶 C,通过磷酸化控制其他蛋白质的功能,从而间接触发 TSPAN18。

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

通过抑制蛋白质合成,环己亚胺可间接激活 TSPAN18。

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

地塞米松可通过影响各种细胞过程(包括免疫反应、炎症、细胞生长和分化)间接刺激 TSPAN18。

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

通过抑制 mTOR,雷帕霉素可能会影响蛋白质合成和细胞生长,从而间接激活 TSPAN18。

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Wortmannin 可抑制磷酸肌酸 3- 激酶(PI3Ks),这可能会通过影响细胞生长和增殖途径间接触发 TSPAN18。

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB203580 可抑制 p38 MAPK,从而影响细胞对应激和炎症的反应,间接刺激 TSPAN18 的活化。

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

染料木素可抑制酪氨酸激酶,从而通过影响多种细胞信号通路间接触发 TSPAN18。

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002抑制PI3K,从而间接激活TSPAN18,影响细胞周期进展和生长。

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 可抑制 c-Jun N 终止子激酶(JNKs),这可能会通过影响对应激信号的反应间接使 TSPAN18 激活。