Date published: 2026-5-13

1-800-457-3801

SCBT Portrait Logo
Seach Input

ET-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of ET-1 monoclonal antibodies for research focused on understanding endothelin-1 in various biological processes. ET-1 monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Endothelin-1 is a potent vasoconstrictor peptide that plays a critical role in regulating vascular tone and blood pressure. Beyond vascular regulation, endothelin-1 influences cardiovascular function, cancer progression, and inflammatory responses. Research has shown that endothelin-1 signaling pathways are crucial targets for therapeutic interventions in various diseases. Scientists studying endothelin-1 can utilize specific detection methods to examine its expression patterns and interactions with other molecules. Understanding endothelin-1 mechanisms continues to reveal new insights into disease development and potential treatments. Investigating endothelin-1 function helps advance knowledge about cardiovascular disorders and cancer biology. Santa Cruz Biotechnology monoclonal antibodies for ET-1 research support scientists worldwide in advancing our understanding of disease mechanisms and developing new therapeutic strategies.

SEE ALSO...

ET-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Endothelin-1/EDN1/ET-1 Antibody (C7)

sc-517436mouse IgG2b κ53-90 (h)WB, IP, IF, IHC(P), ELISAh
3
(4)

Endothelin-1/EDN1/ET-1 Antibody (1C10)

sc-57116mouse IgG1 κ1-21 (h)ELISAh
1
(1)

ET-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Endothelin-1/EDN1/ET-1 CRISPR/Cas9 KO Plasmid (h)

sc-400564hGene KnockoutGFP0
(0)

Endothelin-1/EDN1/ET-1 HDR Plasmid (h)

sc-400564-HDRhHomology Directed RepairPuromycin0
(0)

Endothelin-1/EDN1/ET-1 Double Nickase Plasmid (h)

sc-400564-NIChGene KnockoutPuromycin0
(0)

Endothelin-1/EDN1/ET-1 Double Nickase Plasmid (h2)

sc-400564-NIC-2hGene KnockoutPuromycin0
(0)

ET-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Endothelin-1/EDN1/ET-1 CRISPR Activation Plasmid (h)

sc-400564-ACThGene ActivationPuro, Blast, Hygro0
(0)

Endothelin-1/EDN1/ET-1 CRISPR Activation Plasmid (h2)

sc-400564-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ET-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Endothelin-1/EDN1/ET-1 siRNA (h)

sc-45394hGene SilencingN/A
5
(0)

Endothelin-1/EDN1/ET-1 shRNA Plasmid (h)

sc-45394-SHhGene SilencingPuromycin
5
(0)

Endothelin-1/EDN1/ET-1 shRNA (h) Lentiviral Particles

sc-45394-VhGene SilencingPuromycin
5
(0)

Endothelin-1/EDN1/ET-1 siRNA (m)

sc-45395mGene SilencingN/A
2
(0)

Endothelin-1/EDN1/ET-1 shRNA Plasmid (m)

sc-45395-SHmGene SilencingPuromycin
2
(0)

Endothelin-1/EDN1/ET-1 shRNA (m) Lentiviral Particles

sc-45395-VmGene SilencingPuromycin
2
(0)

Endothelin-1/EDN1/ET-1 siRNA (r)

sc-270091rGene SilencingN/A0
(0)

Endothelin-1/EDN1/ET-1 shRNA Plasmid (r)

sc-270091-SHrGene SilencingPuromycin0
(0)

Endothelin-1/EDN1/ET-1 shRNA (r) Lentiviral Particles

sc-270091-VrGene SilencingPuromycin0
(0)