Ribosomal Protein L18 Antibody (3D5): sc-293359
- Ribosomal Protein L18 Antibody (3D5) is a mouse monoclonal IgG2a κ Ribosomal Protein L18 antibody provided at 100 µg/ml
- raised against amino acids 90-188 of Ribosomal Protein L18 of human origin
- recommended for detection of Ribosomal Protein L18 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ribosomal Protein L18 Antibody (3D5). This work is in progress.
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Ribosomal Protein L18 Antibody (3D5) is a mouse monoclonal IgG2a kappa light chain antibody that detects Ribosomal Protein L18 (RPL18) of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-RPL18 antibody (3D5) is available as the non-conjugated format. RPL18 is a crucial component of the 60S ribosomal subunit, consisting of 188 amino acids and primarily located in the cytoplasm, where RPL18 plays a vital role in protein translation. RPL18 (3D5) monoclonal antibody enables research into the assembly and stability of ribosomes, which synthesize proteins critical for cellular function and growth. Disruptions in ribosomal protein function can lead to various diseases, including cancer and ribosomopathies, highlighting the significance of studying RPL18. The gene encoding RPL18 is located on human chromosome 19, a region that also harbors several immunoglobulin superfamily members, indicating potential involvement in immune responses. Anti-RPL18 antibody (3D5) serves as an invaluable tool for researchers investigating protein synthesis mechanisms and ribosomal dysfunction implications in human health.
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Ribosomal Protein L18 Antibody (3D5) References:
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- The molecular mechanics of eukaryotic translation. | Kapp, LD. and Lorsch, JR. 2004. Annu Rev Biochem. 73: 657-704. PMID: 15189156
- Biological significance of 5S rRNA import into human mitochondria: role of ribosomal protein MRP-L18. | Smirnov, A., et al. 2011. Genes Dev. 25: 1289-305. PMID: 21685364
- Translational control of the cytosolic stress response by mitochondrial ribosomal protein L18. | Zhang, X., et al. 2015. Nat Struct Mol Biol. 22: 404-10. PMID: 25866880
- Dengue virus NS1 protein interacts with the ribosomal protein RPL18: this interaction is required for viral translation and replication in Huh-7 cells. | Cervantes-Salazar, M., et al. 2015. Virology. 484: 113-126. PMID: 26092250
- S-adenosylmethionine inhibits la ribonucleoprotein domain family member 1 in murine liver and human liver cancer cells. | Ramani, K., et al. 2022. Hepatology. 75: 280-296. PMID: 34449924
- Aberrant mitochondrial homeostasis at the crossroad of musculoskeletal ageing and non-small cell lung cancer. | Prokopidis, K., et al. 2022. PLoS One. 17: e0273766. PMID: 36067173
- Decreased expression of RPL15 and RPL18 exacerbated the calcification of valve interstitial cells during aortic valve calcification. | Wang, G., et al. 2023. Cell Biol Int. 47: 1749-1759. PMID: 37431269
- Nucleotide and deduced amino acid sequence of human ribosomal protein L18. | Puder, M., et al. 1993. Biochim Biophys Acta. 1216: 134-6. PMID: 8218404
- Structure and evolution of mammalian ribosomal proteins. | Wool, IG., et al. 1995. Biochem Cell Biol. 73: 933-47. PMID: 8722009
- A map of 75 human ribosomal protein genes. | Kenmochi, N., et al. 1998. Genome Res. 8: 509-23. PMID: 9582194
- Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18. | Kumar, KU., et al. 1999. Mol Cell Biol. 19: 1116-25. PMID: 9891046
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ribosomal Protein L18 Antibody (3D5) | sc-293359 | 100 µg/ml | $316.00 |