PNO1 Antibody (A-3): sc-514905

PNO1 Antibody (A-3) is a mouse monoclonal IgG2b antibody that detects PNO1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PNO1, also known as KHRBP1, is a 252 amino acid protein that plays a crucial role in RNA binding events during transcription and translation, which are essential processes for gene expression and cellular function. PNO1 is primarily localized in the nucleolus, a subnuclear structure involved in ribosome biogenesis and the processing of precursor ribosomal RNA. This localization is significant because PNO1 participates in the regulation of ribosomal RNA synthesis and the assembly of ribosomal subunits, which are vital for protein synthesis in all living cells. The gene encoding PNO1 is located on human chromosome 2, a region that contains over 1,400 genes and represents nearly 8% of the human genome, underscoring PNO1′s importance in various biological processes. Anti-PNO1 antibody (A-3) is an invaluable tool for researchers studying the intricate mechanisms of RNA metabolism and its implications in health and disease.

The preferred PNO1 antibody is PNO1 Antibody (G-7): sc-514727.