Molecular structure of 2-Hydroxycinnamaldehyde, CAS Number: 3541-42-2
2-Hydroxycinnamaldehyde (CAS 3541-42-2)
See product citations (5)
Alternate Names:
3-(2-Hydroxyphenyl)-2-propenal
CAS Number:
3541-42-2
Molecular Weight:
148.16
Molecular Formula:
C9H8O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2-Hydroxycinnamaldehyde exhibits antioxidant properties by effectively neutralizing harmful free radicals and reactive oxygen species, which have the potential to harm cells. Additionally, this compound has the ability to suppress the production of pro-inflammatory cytokines. Furthermore, 2-Hydroxycinnamaldehyde demonstrates the capacity to impede the growth of cancer cells through the induction of apoptosis, a process involving programmed cell death.
2-Hydroxycinnamaldehyde (CAS 3541-42-2) References
- Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. | Choi, J., et al. 2001. Arch Pharm Res. 24: 418-23. PMID: 11693543
- Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents. | Shin, DS., et al. 2006. Bioorg Med Chem. 14: 2498-506. PMID: 16343908
- Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention. | Chew, EH., et al. 2010. Free Radic Biol Med. 48: 98-111. PMID: 19837157
- 2-Hydroxycurcuminoid induces apoptosis of human tumor cells through the reactive oxygen species-mitochondria pathway. | Han, YM., et al. 2011. Bioorg Med Chem Lett. 21: 747-51. PMID: 21183341
- Antitumor activity of 2-hydroxycinnamaldehyde for human colon cancer cells through suppression of β-catenin signaling. | Lee, MA., et al. 2013. J Nat Prod. 76: 1278-84. PMID: 23855266
- A new coumarin and cytotoxic activities of constituents from Cinnamomum cassia. | Ngoc, TM., et al. 2014. Nat Prod Commun. 9: 487-8. PMID: 24868863
- Diversity-Oriented One-Pot Synthesis to Construct Functionalized Chroman-2-one Derivatives and Other Heterocyclic Compounds. | Chen, YH., et al. 2017. J Org Chem. 82: 4774-4783. PMID: 28421761
- A Bioinspired Cascade Sequence Enables Facile Assembly of Methanodibenzo[b,f][1,5]dioxocin Flavonoid Scaffold. | Liu, H., et al. 2018. Org Lett. 20: 546-549. PMID: 29345470
- Up-regulation of Bone Morphogenetic Protein 7 by 2-Hydroxycinnamaldehyde Attenuates HNSCC Cell Invasion. | Kang, SM., et al. 2018. Anticancer Res. 38: 5747-5757. PMID: 30275196
- Synthesis and biological activity of cinnamaldehydes as angiogenesis inhibitors | Byoung-Mog Kwon, Seung-Ho Lee, Young-Kwon Cho, Song-Hae Bok, Seung-Ho So, Mi-Ran Youn, Soo-Ik Chang. 1997. Bioorganic & Medicinal Chemistry Letters. Volume 7, Issue 19: 2473-2476.
- Antitumor activity of 2-hydroxycinnamaldehyde against human colorectal cancer cells is mediated by the Wnt/β-catenin signaling pathway | Won Kyung Kim;, et al. 2014. Cancer Res. 74: 4237.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Hydroxycinnamaldehyde, 1 g | sc-288153 | 1 g | $764.00 |