Date published: 2025-11-20

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Zoxamide (CAS 156052-68-5)

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Alternate Names:
3,5-Dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-4-methylbenzamide; RH 7281; Zoxium
CAS Number:
156052-68-5
Molecular Weight:
336.64
Molecular Formula:
C14H16Cl3NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Zoxamide acts as a fungicide and within the agricultural sector for the management of specific crop infestation. It falls under the category of sulfonylureas, a group of fungicides utilized for the control of fungal infestation in crops. Zoxamide′s mechanism of action involves the inhibition of acetolactate synthase (ALS), an enzyme for the synthesis of branched-chain amino acids necessary for fungal growth and development.


Zoxamide (CAS 156052-68-5) References

  1. In vitro mammalian metabolism of the mitosis inhibitor zoxamide and the relationship to its in vitro toxicity.  |  Oesch, F., et al. 2010. Xenobiotica. 40: 72-82. PMID: 20001673
  2. Proteomic analysis of zoxamide-induced changes in Phytophthora cactorum.  |  Mei, X., et al. 2014. Pestic Biochem Physiol. 113: 31-9. PMID: 25052524
  3. Proteomic analysis on zoxamide-induced sensitivity changes in Phytophthora cactorum.  |  Mei, X., et al. 2015. Pestic Biochem Physiol. 123: 9-18. PMID: 26267047
  4. C239S Mutation in the β-Tubulin of Phytophthora sojae Confers Resistance to Zoxamide.  |  Cai, M., et al. 2016. Front Microbiol. 7: 762. PMID: 27242773
  5. The fate and enantioselective behavior of zoxamide during wine-making process.  |  Pan, X., et al. 2018. Food Chem. 248: 14-20. PMID: 29329837
  6. A systematic evaluation of zoxamide at enantiomeric level.  |  Pan, X., et al. 2020. Sci Total Environ. 733: 139069. PMID: 32446056
  7. Assessing the toxicity of the benzamide fungicide zoxamide in zebrafish (Danio rerio): Towards an adverse outcome pathway for beta-tubulin inhibitors.  |  Zhang, X., et al. 2020. Environ Toxicol Pharmacol. 78: 103405. PMID: 32446185
  8. Peer review of the pesticide risk assessment of the active substance zoxamide.  |  , ., et al. 2017. EFSA J. 15: e04980. PMID: 32625645
  9. Effective Remediation Strategy for Xenobiotic Zoxamide by Pure Bacterial Strains, Escherichia coli, Streptococcus pyogenes, and Streptococcus pneumoniae.  |  Ahmad, KS., et al. 2020. Biomed Res Int. 2020: 5352427. PMID: 33224979
  10. Zoxamide accumulation and retention evaluation after nanosuspension technology application in tomato plant.  |  Corrias, F., et al. 2021. Pest Manag Sci. 77: 3508-3518. PMID: 33837628
  11. Toxicological Comparison of Mancozeb and Zoxamide Fungicides at Environmentally Relevant Concentrations by an In Vitro Approach.  |  Lori, G., et al. 2021. Int J Environ Res Public Health. 18: PMID: 34444340
  12. Removal of azimsulfuron and zoxamide using a tapered variable diameter biological fluidized bed combined with electrochemistry: Mass fraction division, energy metabolism activity and carbon emissions.  |  Yu, L., et al. 2022. Bioresour Technol. 346: 126518. PMID: 34896261
  13. Assessment of the eco-toxicological effects in zoxamide polluted soil amended with fertilizers-An indoor evaluation.  |  Liu, H., et al. 2022. Chemosphere. 301: 134630. PMID: 35447215

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Zoxamide, 50 mg

sc-474628
50 mg
$108.00