Molecular structure of Uridine, CAS Number: 58-96-8
Uridine (CAS 58-96-8)
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Alternate Names:
1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside; D-Uridine
Application:
Uridine is a nucleoside and one of main component in RNA
CAS Number:
58-96-8
Purity:
≥99%
Molecular Weight:
244.20
Molecular Formula:
C9H12N2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Uridine, an essential nucleoside, encompasses a nitrogenous base, a sugar, and a phosphate group, constituting a type of organic compound. It serves as a fundamental building block of RNA and is naturally present in various food sources like mushrooms, brewer′s yeast, and beer. The multifaceted roles of uridine within the body have been extensively investigated in recent years. Uridine is believed to engage in several mechanisms, including the modulation of synaptic plasticity, neuronal excitability, and cell proliferation. Moreover, it is thought to modulate the activity of numerous enzymes, such as phospholipase C, adenylate cyclase, and protein kinase C.
Uridine (CAS 58-96-8) References
- Uridine and its nucleotides: biological actions, therapeutic potentials. | Connolly, GP. and Duley, JA. 1999. Trends Pharmacol Sci. 20: 218-25. PMID: 10354618
- Modulation of fluorouracil toxicity with uridine. | van Groeningen, CJ., et al. 1992. Semin Oncol. 19: 148-54. PMID: 1557641
- Uridine binding by Zn(II) macrocyclic complexes: diversion of RNA cleavage catalysts. | Rossiter, CS., et al. 2005. Inorg Chem. 44: 9397-404. PMID: 16323926
- Biochemistry of uridine in plasma. | Yamamoto, T., et al. 2011. Clin Chim Acta. 412: 1712-24. PMID: 21689643
- Quantitative determination of uridine in rabbit plasma and urine by liquid chromatography coupled to a tandem mass spectrometry. | Kang, W. 2012. Biomed Chromatogr. 26: 541-4. PMID: 22392515
- QM/MM and MM MD Simulations on the Pyrimidine-Specific Nucleoside Hydrolase: A Comprehensive Understanding of Enzymatic Hydrolysis of Uridine. | Fan, F., et al. 2018. J Phys Chem B. 122: 1121-1131. PMID: 29285933
- Anomalous interaction of tri-acyl ester derivatives of uridine nucleoside with a l-α-dimyristoylphosphatidylcholine biomembrane model: a differential scanning calorimetry study. | Berrío Escobar, JF., et al. 2019. J Pharm Pharmacol. 71: 329-337. PMID: 30456846
- Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus. | Krol, E., et al. 2019. Molecules. 24: PMID: 30901934
- Uridine natural products: Challenging targets and inspiration for novel small molecule inhibitors. | Arbour, CA. and Imperiali, B. 2020. Bioorg Med Chem. 28: 115661. PMID: 32828427
- Uridine alleviates carbon tetrachloride-induced liver fibrosis by regulating the activity of liver-related cells. | Zheng, WV., et al. 2022. J Cell Mol Med. 26: 840-854. PMID: 34970843
- Recognition and release of uridine and hCNT3: From multivariate interactions to molecular design. | Duan, H., et al. 2022. Int J Biol Macromol. 223: 1562-1577. PMID: 36402394
- Uridine transport and metabolism in the central nervous system. | Spector, R. 1985. J Neurochem. 45: 1411-8. PMID: 3930662
- Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity. | Leyva, A., et al. 1984. Cancer Res. 44: 5928-33. PMID: 6498850
- Uridine regulation by the isolated rat liver: perfusion with an artificial oxygen carrier. | Monks, A. and Cysyk, RL. 1982. Am J Physiol. 242: R465-70. PMID: 7081472
Inhibitor of:
DEPDC5, Rab L4, UPase, and UTP14C.Activator of:
β-1,3-Gal-T2, β-1,4-Gal-T5, 4933425L06Rik, 5′-nucleotidase, 8-oxoG DNA Lesion, AK3, ALG12, ALKBH8, AQR, CDD, CHPT1, CIRH1A, CMAS, CNT1, CNT2, CNT3, CTPS2, CWH43, DPYS, Edc4, ENT2, ENT3, ENT4, FLJ23356, GALK2, GLT25D2, GPR17, Hep C NS5a, HPV18 E7, IMP-3, Influenza B, NANS, NGF, NT5C3, PANK1, PEMT, PIG-N, PUS7, RBM23, Ribosomal Protein S25, RPL7A, SKIV2L2, SLC17A4, Slc5a11, SRP14, St3Gal-IV, TK2, TS, UAP1, UCK1, UTP14C, VpreB, and WDR92.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Uridine, 1 g | sc-296685 | 1 g | $60.00 | |||
Uridine, 25 g | sc-296685A | 25 g | $98.00 |