Date published: 2025-10-8

1-800-457-3801

SCBT Portrait Logo
Seach Input

Trimethylpyruvic acid (CAS 815-17-8)

5.0(1)
Write a reviewAsk a question

Alternate Names:
3,3-Dimethyl-2-oxobutyric acid
CAS Number:
815-17-8
Molecular Weight:
130.14
Molecular Formula:
C6H10O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Trimethylpyruvic acid is a colorless liquid characterized by a potent odor. Its synthesis involves the oxidation of l-tert-leucine using hydrogen peroxide in the presence of sodium hydroxide. Due to its chirality, this compound can exist in two distinct forms with varying physical and chemical attributes. Trimethylpyruvic acid can be used as a precursor in the synthesis of diverse molecules like amides, carboxylic acids, and nucleotides. Additionally, it has photochemical properties making it suitable for reactions requiring heating or light.


Trimethylpyruvic acid (CAS 815-17-8) References

  1. Solid-phase/solution-phase combinatorial synthesis of neuroimmunophilin ligands.  |  Rabinowitz, M., et al. 2000. Bioorg Med Chem Lett. 10: 1007-10. PMID: 10843203
  2. Diphosphanylketenimines: new reagents for the synthesis of unique phosphorus heterocycles.  |  Ruiz, J., et al. 2002. Chemistry. 8: 3872-8. PMID: 12360928
  3. Artificial multienzyme supramolecular device: highly ordered self-assembly of oligomeric enzymes in vitro and in vivo.  |  Gao, X., et al. 2014. Angew Chem Int Ed Engl. 53: 14027-30. PMID: 25319901
  4. Construction of a tunable multi-enzyme-coordinate expression system for biosynthesis of chiral drug intermediates.  |  Jiang, W. and Fang, B. 2016. Sci Rep. 6: 30462. PMID: 27456301
  5. Rational Engineering of Bacillus cereus Leucine Dehydrogenase Towards α-keto Acid Reduction for Improving Unnatural Amino Acid Production.  |  Zhou, J., et al. 2019. Biotechnol J. 14: e1800253. PMID: 30052323
  6. Efficient Hyperpolarization of U-13 C-Glucose Using Narrow-Line UV-Generated Labile Free Radicals.  |  Capozzi, A., et al. 2019. Angew Chem Int Ed Engl. 58: 1334-1339. PMID: 30515929
  7. Electrochemical hydrogenation of non-aromatic carboxylic acid derivatives as a sustainable synthesis process: from catalyst design to device construction.  |  Sadakiyo, M., et al. 2019. Phys Chem Chem Phys. 21: 5882-5889. PMID: 30865734
  8. Enzymes for pharmaceutical and therapeutic applications.  |  Meghwanshi, GK., et al. 2020. Biotechnol Appl Biochem. 67: 586-601. PMID: 32248597
  9. Cloning and Expression of a Novel Leucine Dehydrogenase: Characterization and L-tert-Leucine Production.  |  Luo, W., et al. 2020. Front Bioeng Biotechnol. 8: 186. PMID: 32296684
  10. Engineering bi-functional enzyme complex of formate dehydrogenase and leucine dehydrogenase by peptide linker mediated fusion for accelerating cofactor regeneration.  |  Zhang, Y., et al. 2017. Eng Life Sci. 17: 989-996. PMID: 32624849
  11. Construction and characterization of a novel glucose dehydrogenase-leucine dehydrogenase fusion enzyme for the biosynthesis of L-tert-leucine.  |  Liao, L., et al. 2021. Microb Cell Fact. 20: 3. PMID: 33407464
  12. Expression of Novel L-Leucine Dehydrogenase and High-Level Production of L-Tert-Leucine Catalyzed by Engineered Escherichia coli.  |  Jia, YY., et al. 2021. Front Bioeng Biotechnol. 9: 655522. PMID: 33859982
  13. Synthesis of indolo[2,1-α]isoquinoline derivatives via metal-free radical cascade cyclization.  |  Hu, XY., et al. 2021. Org Biomol Chem. 19: 10376-10384. PMID: 34812822
  14. Absorption and emission spectroscopy of pyruvic acids and pyruvate esters.  |  Arnett, JF., et al. 1973. J Am Chem Soc. 95: 7599-603. PMID: 4759034
  15. The biosynthesis of tyrosine from labeled glucose in Escherichia coli.  |  Sprecher, M., et al. 1965. Biochemistry. 4: 2855-60. PMID: 5326357

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Trimethylpyruvic acid, 50 g

sc-280155
50 g
$94.00

What about the concentration with mM? I dont the concentration

Asked by: Gamal
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-04-29
  • y_2025, m_9, d_24, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_280155, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 98ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from ConcentrationWhat about the concentration with mM? i dont the concentration
Date published: 2022-03-03
  • y_2025, m_9, d_24, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_280155, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
Trimethylpyruvic acid is rated 5.0 out of 5 by 1.
  • y_2025, m_9, d_24, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_280155, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 99ms
  • REVIEWS, PRODUCT