Molecular structure of Triadimenol, CAS Number: 55219-65-3
Triadimenol (CAS 55219-65-3)
Application:
Triadimenol is a triazole-type anti-fungal demonstrating estrogen receptor agonism
CAS Number:
55219-65-3
Purity:
≥96%
Molecular Weight:
295.76
Molecular Formula:
C14H18ClN3O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Triadimenol is a fungicide that functions by inhibiting the biosynthesis of ergosterol in fungal cells. It acts as a demethylation inhibitor, specifically targeting the 14α-demethylase enzyme. By doing so, it disrupts the integrity of the fungal cell membrane, leading to the inhibition of mycelial growth and spore germination. This mechanism of action ultimately results in the suppression of fungal diseases in various crops. Triadimenol′s mechanism of action involves binding to the heme group of the 14α-demethylase enzyme, thereby preventing the conversion of lanosterol to ergosterol. This disruption in ergosterol production compromises the structural integrity and function of the fungal cell membrane, leading to the inhibition of fungal growth and reproduction.
Triadimenol (CAS 55219-65-3) References
- Separation of triadimefon and triadimenol enantiomers and diastereoisomers by supercritical fluid chromatography. | del Nozal, MJ., et al. 2003. J Chromatogr A. 986: 135-41. PMID: 12585331
- Stereoselective degradation of fungicide triadimenol in cucumber plants. | Dong, F., et al. 2010. Chirality. 22: 292-8. PMID: 19496157
- Development and application of a physiologically based pharmacokinetic model for triadimefon and its metabolite triadimenol in rats and humans. | Crowell, SR., et al. 2011. Toxicol Lett. 205: 154-62. PMID: 21641977
- Stereoselective transformation of triadimefon to metabolite triadimenol in wheat and soil under field conditions. | Liang, H., et al. 2013. J Hazard Mater. 260: 929-36. PMID: 23876258
- Developmental exposures to an azole fungicide triadimenol at environmentally relevant concentrations cause reproductive dysfunction in females of medaka fish. | Chu, SH., et al. 2016. Chemosphere. 152: 181-9. PMID: 26971170
- Tissue distribution and metabolism of triadimefon and triadimenol enantiomers in Chinese lizards (Eremias argus). | Li, J., et al. 2017. Ecotoxicol Environ Saf. 142: 284-292. PMID: 28433593
- Chronic exposure to triadimenol at environmentally relevant concentration adversely affects aging biomarkers in Caenorhabditis elegans associated with insulin/IGF-1 signaling pathway. | How, CM., et al. 2018. Sci Total Environ. 640-641: 485-492. PMID: 29864662
- Degradation of triadimefon and residue levels of metabolite triadimenol: tracing rapeseed from harvesting and storage to household oil processing. | Li, Y., et al. 2019. J Sci Food Agric. 99: 1484-1491. PMID: 30126020
- Microbiological and biochemical properties of soil polluted with a mixture of spiroxamine, tebuconazole, and triadimenol under the cultivation of Triticum aestivum L. | Baćmaga, M., et al. 2019. Environ Monit Assess. 191: 416. PMID: 31172361
- Stereoselective behaviors of the fungicide triadimefon and its metabolite triadimenol during malt storage and beer brewing. | Kong, Z., et al. 2020. J Hazard Mater. 400: 123238. PMID: 32947687
- Levels of residues and dietary risk assessment of the fungicides myclobutanil, penconazole, tebuconazole, and triadimenol in squash. | Abdallah, OI., et al. 2021. Biomed Chromatogr. 35: e5126. PMID: 33772827
- Stochastic dynamic ultraviolet photofragmentation and high collision energy dissociation mass spectrometric kinetics of triadimenol and sucralose. | Ivanova, B. and Spiteller, M. 2022. Environ Sci Pollut Res Int.. PMID: 36462070
- Triadimenol promotes the production of reactive oxygen species and apoptosis with cardiotoxicity and developmental abnormalities in zebrafish. | Park, J., et al. 2023. Sci Total Environ. 862: 160761. PMID: 36502969
Activator of:
Estrogen Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Triadimenol, 10 g | sc-205871 | 10 g | $116.00 | |||
Triadimenol, 25 g | sc-205871A | 25 g | $237.00 |