Molecular structure of Tocopherylquinone, d-alpha, CAS Number: 7559-04-8
Tocopherylquinone, d-alpha (CAS 7559-04-8)
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Application:
Tocopherylquinone, d-alpha is a vitaman E oxidation product with antioxidant activities
CAS Number:
7559-04-8
Purity:
95%
Molecular Weight:
446.7
Molecular Formula:
C29H50O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Tocopherylquinone, d-alpha is an alpha-tocopherol oxidation product. During hypoxia in rats, levels of tocopherylquinon have been found to rise. It is reported to downregulate respiratory acitvity of mitochondria. It has also displayed antioxidant activities after it is reduced to tocopherylhydroquinone.
Tocopherylquinone, d-alpha (CAS 7559-04-8) References
- Determination of alpha-tocopherol and alpha-tocopherylquinone in rat tissues and plasma by high-performance liquid chromatography with electrochemical detection. | Kanazawa, H., et al. 2000. Chem Pharm Bull (Tokyo). 48: 1462-6. PMID: 11045451
- Redox-interaction of alpha-tocopheryl quinone with isolated mitochondrial cytochrome bc1 complex. | Gille, L., et al. 2004. Biochem Pharmacol. 68: 373-81. PMID: 15194009
- Tocopherylquinone d-alpha an oxidized form of vitamin E increases mitochondrial uncoupling protein 2 expression in human umbilical vein endothelial cells in vitro. | Cheong, YM., et al. 2010. Int J Cardiol. 145: 562-3. PMID: 20550972
- The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant. | Siegel, D., et al. 1997. Mol Pharmacol. 52: 300-5. PMID: 9271353
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tocopherylquinone, d-alpha, 20 mg | sc-200821 | 20 mg | $65.00 | |||
Tocopherylquinone, d-alpha, 100 mg | sc-200821A | 100 mg | $137.00 |