Molecular structure of Thymidine, CAS Number: 50-89-5
Thymidine (CAS 50-89-5)
See product citations (16)
Alternate Names:
Thymidine is also known as Thymine deoxyriboside.
Application:
Thymidine is a pyrimidine deoxynucleoside
CAS Number:
50-89-5
Purity:
>98%
Molecular Weight:
242.23
Molecular Formula:
C10H14N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Thymidine is a pyrimidine deoxynucleoside which pairs with deoxyadenosine in double-stranded DNA. Thymidine is a nucleoside composed of a pentose sugar, deoxyribose, and a pyrimidine base thymine. Phosphorylation of thymidine with one, two or three phosphoric acid groups, can form dTMP (deoxythymidine monophosphate), dTDP, or dTTP. Thymidine has been used in cell synchronization in G1/early S phase, to incubate cells in cell-cycle analysis, and as a supplement in HL5-modified medium for cell culture.
Thymidine (CAS 50-89-5) References
- Excited-state properties of thymidine and their relevance to its heterogeneous emission in double-stranded DNA. | Georghiou, S. and Gerke, LS. 1999. Photochem Photobiol. 69: 646-52. PMID: 10378002
- Synthesis and biological evaluation of 3'-carboranyl thymidine analogues. | Yan, J., et al. 2002. Bioorg Med Chem Lett. 12: 2209-12. PMID: 12127539
- Synthesis of 1,4-anhydro-2-deoxy-D-ribitol derivatives from thymidine. | Serebryany, V. and Beigelman, L. 2003. Nucleosides Nucleotides Nucleic Acids. 22: 1305-7. PMID: 14565405
- Glycosidic bond cleavage of thymidine by low-energy electrons. | Zheng, Y., et al. 2004. J Am Chem Soc. 126: 1002-3. PMID: 14746451
- The synthesis and biochemical evaluation of thymidine analogues substituted with nido carborane at the N-3 position. | Byun, Y., et al. 2004. Appl Radiat Isot. 61: 1125-30. PMID: 15308203
- Independent generation of C5'-nucleosidyl radicals in thymidine and 2'-deoxyguanosine. | Manetto, A., et al. 2007. J Org Chem. 72: 3659-66. PMID: 17425368
- Carboranyl thymidine analogues for neutron capture therapy. | Tjarks, W., et al. 2007. Chem Commun (Camb). 4978-91. PMID: 18049729
- Exploring the potential of 3'-O-carboxy esters of thymidine as inhibitors of ribonuclease A and angiogenin. | Ghosh, KS., et al. 2008. Bioorg Med Chem. 16: 2819-28. PMID: 18226913
- Organometallic [Re(CO)3]+ and [Re(CO)2(NO)]2+ labeled substrates for human thymidine kinase 1. | Struthers, H., et al. 2009. Inorg Chem. 48: 5154-63. PMID: 19400575
- Precise site-selective termination of DNA replication by caging the 3-position of thymidine and its application to polymerase chain reaction. | Kuzuya, A., et al. 2009. Bioconjug Chem. 20: 1924-9. PMID: 19780524
- Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine. | San Pedro, JM. and Greenberg, MM. 2012. Org Lett. 14: 2866-9. PMID: 22616940
- Reaction of Thymidine with Hypobromous Acid in Phosphate Buffer. | Suzuki, T., et al. 2016. Chem Pharm Bull (Tokyo). 64: 1235-8. PMID: 27477666
- Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops. | Virgilio, A., et al. 2018. Sci Rep. 8: 7447. PMID: 29749406
- Pathways of thymidine hypermodification. | Lee, YJ., et al. 2022. Nucleic Acids Res. 50: 3001-3017. PMID: 34522950
Inhibitor of:
Dbf4b, DNA pol ε 4, DPYD, LOC643909, MB21D2, MFT, RCC2, RFC2, and UPase.Activator of:
γ-GCSc, 4933425L06Rik, ADO, API5, ART1, ART2A, ART2B, Bir1, C8orf80, Cdc25B, Cdc5, CMPK, CNT1, CNT2, DCTD, DHFRL1, DTYMK, dUTPase, ENT2, ENT3, FucT-X, Gap 1, HiNF-P, HIRIP3, HISPPD2A, HSV-1 UL42, IBRDC1, Kin28, LIN-35, LOC643862, MCM-BP, ORC4, ORC5, ORC6, PARP-6, PD-ECGF, RmlB, scc-112_Pds5a, SPHAR, TDP1, TK2, TS, UCK1, UDG2, and ZYG11A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thymidine, 1 g | sc-296542 | 1 g | $48.00 | |||
Thymidine, 5 g | sc-296542A | 5 g | $72.00 | |||
Thymidine, 25 g | sc-296542B | 25 g | $112.00 | |||
Thymidine, 100 g | sc-296542C | 100 g | $265.00 | |||
Thymidine, 250 g | sc-296542D | 250 g | $449.00 | |||
Thymidine, 1 kg | sc-296542E | 1 kg | $1724.00 |