Date published: 2025-10-3

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Tetraglyme (CAS 143-24-8)

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Alternate Names:
Tetraethylene Glycol Dimethyl Ether; Bis[2-(2-methoxyethoxy)ethyl] Ether; 2,5,8,11,14-Pentaoxapentadecane
Application:
Tetraglyme is a polar polyether solvent
CAS Number:
143-24-8
Molecular Weight:
222.28
Molecular Formula:
C10H22O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tetraglyme, also known as tetraethylene glycol dimethyl ether, is a colorless, odorless liquid with a high boiling point and low vapor pressure. It is a stable compound that is used as a solvent in various chemical processes. Tetraglyme′s ability to dissolve a wide range of substances, making it a versatile in biochemistry. Tetraglyme is used as a reaction medium for organic and inorganic reactions. Tetraglyme is also utilized as an electrolyte in lithium-ion batteries, due to its high dielectric constant and thermal stability. It is used as a component in the formulation of electrolytes for supercapacitors and fuel cells.


Tetraglyme (CAS 143-24-8) References

  1. Evaluation of tetraglyme for the enrichment and analysis of volatile organic compounds in air.  |  Huybrechts, T., et al. 2001. J Chromatogr A. 922: 207-18. PMID: 11486865
  2. PEO-like plasma polymerized tetraglyme surface interactions with leukocytes and proteins: in vitro and in vivo studies.  |  Shen, M., et al. 2002. J Biomater Sci Polym Ed. 13: 367-90. PMID: 12160299
  3. Plasma deposition of tetraglyme inside small diameter tubing: optimization and characterization.  |  Cao, L., et al. 2007. J Biomed Mater Res A. 81: 12-23. PMID: 17109409
  4. Plasma-deposited tetraglyme surfaces greatly reduce total blood protein adsorption, contact activation, platelet adhesion, platelet procoagulant activity, and in vitro thrombus deposition.  |  Cao, L., et al. 2007. J Biomed Mater Res A. 81: 827-37. PMID: 17236214
  5. Tetraglyme coatings reduce fibrinogen and von Willebrand factor adsorption and platelet adhesion under both static and flow conditions.  |  Zhang, M. and Horbett, TA. 2009. J Biomed Mater Res A. 89: 791-803. PMID: 18496865
  6. The role of complement C3 and fibrinogen in monocyte adhesion to PEO-like plasma deposited tetraglyme.  |  Szott, LM. and Horbett, TA. 2010. J Biomed Mater Res A. 95: 1252-60. PMID: 20939050
  7. Tetraglyme-mediated synthesis of Pd nanoparticles for dehydrogenation of ammonia borane.  |  Kim, SK., et al. 2012. Chem Commun (Camb). 48: 2021-3. PMID: 22234607
  8. A novel rechargeable battery with a magnesium anode, a titanium dioxide cathode, and a magnesium borohydride/tetraglyme electrolyte.  |  Su, S., et al. 2015. Chem Commun (Camb). 51: 2641-4. PMID: 25571942
  9. Li(+) Local Structure in Li-Tetraglyme Solvate Ionic Liquid Revealed by Neutron Total Scattering Experiments with the (6/7)Li Isotopic Substitution Technique.  |  Saito, S., et al. 2016. J Phys Chem Lett. 7: 2832-7. PMID: 27388117
  10. Interface structure between tetraglyme and graphite.  |  Minato, T., et al. 2017. J Chem Phys. 147: 124701. PMID: 28964018
  11. Binary Mixtures of Highly Concentrated Tetraglyme and Hydrofluoroether as a Stable and Nonflammable Electrolyte for Li-O2 Batteries.  |  Zhao, Q., et al. 2018. ACS Appl Mater Interfaces. 10: 26312-26319. PMID: 30004208
  12. Insight into the Solvation Structure of Tetraglyme-Based Electrolytes via First-Principles Molecular Dynamics Simulation.  |  Sun, Y. and Hamada, I. 2018. J Phys Chem B. 122: 10014-10022. PMID: 30299952
  13. Investigation of alkali and alkaline earth solvation structures in tetraglyme solvent.  |  Nguyen, LHB., et al. 2021. Phys Chem Chem Phys. 23: 26120-26129. PMID: 34559176
  14. Calcium vapor synthesis of extremely coercive SmCo5.  |  Baker, SE., et al. 2022. RSC Adv. 12: 3721-3728. PMID: 35425363
  15. Investigating the abnormal conductivity behaviour of divalent cations in low dielectric constant tetraglyme-based electrolytes.  |  Nguyen, LHB., et al. 2022. Phys Chem Chem Phys. 24: 21601-21611. PMID: 36004582

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tetraglyme, 250 g

sc-213018
250 g
$68.00

Tetraglyme, 1 kg

sc-213018A
1 kg
$228.00

Tetraglyme, 5 kg

sc-213018B
5 kg
$650.00

Tetraglyme, 10 kg

sc-213018C
10 kg
$1185.00