Date published: 2025-11-20

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Tebufenozide (CAS 112410-23-8)

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Alternate Names:
N-tert-Butyl-N′-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
Application:
Tebufenozide is an ecdysone agonist.
CAS Number:
112410-23-8
Purity:
≥98%
Molecular Weight:
352.47
Molecular Formula:
C22H28N2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tebufenozide is a compound that has garnered interest in agricultural research due to its activity as an insect growth regulator. It is used in studies targeting the control of pest populations, particularly those of the Lepidoptera order. The compound′s mode of action involves mimicking the activity of naturally occurring hormones in insects, disrupting their normal molting process. In ecological research, Tebufenozide is utilized to understand the impact of such regulators on insect lifecycles and their potential effects on non-target organisms within the ecosystem. Additionally, it is used in investigations concerning the development of pest resistance, informing strategies for the sustainable use of growth regulators in integrated pest management programs. Researchers also study the environmental fate of Tebufenozide, including its degradation and persistence in soils and its potential for bioaccumulation.


Tebufenozide (CAS 112410-23-8) References

  1. Tebufenozide disrupts ovarian development and function in silkmoths.  |  Sridhara, S. and Lee, VH. 2013. Insect Biochem Mol Biol. 43: 1087-99. PMID: 24121094
  2. Tebufenozide resistance is associated with sex-linked inheritance in Plutella xylostella.  |  Cao, GC. and Han, ZJ. 2015. Insect Sci. 22: 235-42. PMID: 25813528
  3. Cytotoxic effects of tebufenozide in vitro bioassays.  |  Yu, X., et al. 2016. Ecotoxicol Environ Saf. 129: 180-8. PMID: 27043174
  4. Dissipation and metabolism of tebufenozide in cabbage and soil under open field conditions in South China.  |  Liu, J., et al. 2016. Ecotoxicol Environ Saf. 134P1: 204-212. PMID: 27636325
  5. An investigation into the formation of tebufenozide's toxic aromatic amine metabolites in human in vitro hepatic microsomes.  |  Abass, KM. 2016. Pestic Biochem Physiol. 133: 73-78. PMID: 27742364
  6. Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells.  |  Xu, W., et al. 2017. Environ Toxicol Pharmacol. 49: 89-96. PMID: 27960113
  7. Residue analysis and dietary exposure risk assessment of tebufenozide in stem lettuce (Lactuca sativa L. var. angustana Irish).  |  Lin, H., et al. 2018. Food Chem Toxicol. 120: 64-70. PMID: 29958988
  8. Toxicological and morphological effects of tebufenozide on Anticarsia gemmatalis (Lepidoptera: Noctuidae) larvae.  |  Fiaz, M., et al. 2018. Chemosphere. 212: 337-345. PMID: 30145425
  9. Genome-wide Identification of Tebufenozide Resistant Genes in the smaller tea tortrix, Adoxophyes honmai (Lepidoptera: Tortricidae).  |  Uchibori-Asano, M., et al. 2019. Sci Rep. 9: 4203. PMID: 30862839
  10. Determination, residue analysis, risk assessment and processing factors of tebufenozide in okra fruits under field conditions.  |  Luo, X., et al. 2020. J Sci Food Agric. 100: 1230-1237. PMID: 31696522
  11. The comparative metabolic response of Bactrocera dorsalis larvae to azadirachtin, pyriproxyfen and tebufenozide.  |  Zhou, Y., et al. 2020. Ecotoxicol Environ Saf. 189: 110020. PMID: 31809954
  12. Effects of Topical Tebufenozide Application to Choristoneura fumiferana Pupae (Lepidoptera: Tortricidae).  |  Roscoe, LE., et al. 2020. Insects. 11: PMID: 32183308
  13. Tebufenozide has limited direct effects on simulated aquatic communities.  |  Edge, C., et al. 2022. Ecotoxicology. 31: 1231-1240. PMID: 36083423

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tebufenozide, 100 mg

sc-280110
100 mg
$200.00