Molecular structure of Stearoyl Ethanolamide, CAS Number: 111-57-9
Stearoyl Ethanolamide (CAS 111-57-9)
Alternate Names:
Ceramid; Stearic Acid Ethanolamide
Application:
Stearoyl Ethanolamide is a prolific fatty acid ethanolamide produced by PLD hydrolysis of membrane phospholipids
CAS Number:
111-57-9
Purity:
>98%
Molecular Weight:
327.6
Molecular Formula:
C20H41NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Stearoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called anandamides. Stearoyl ethanolamide is the most prolific of several fatty acid ethanolamides produced by the PLD hydrolysis of murine neuroblastoma cell membrane phospholipids. The specific role of stearoyl ethanolamide in the cannabinergic system is still to be elucidated.
Stearoyl Ethanolamide (CAS 111-57-9) References
- Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. | Maccarrone, M., et al. 2002. Biochem J. 366: 137-44. PMID: 12010121
- Cannabimimetic activity, binding, and degradation of stearoylethanolamide within the mouse central nervous system. | Maccarrone, M., et al. 2002. Mol Cell Neurosci. 21: 126-40. PMID: 12359156
- Stearoylethanolamide exerts anorexic effects in mice via down-regulation of liver stearoyl-coenzyme A desaturase-1 mRNA expression. | Terrazzino, S., et al. 2004. FASEB J. 18: 1580-2. PMID: 15289450
- Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography-tandem mass spectrometry. | Balvers, MG., et al. 2009. J Chromatogr B Analyt Technol Biomed Life Sci. 877: 1583-90. PMID: 19395322
- Palmitoylethanolamide and stearoylethanolamide levels in the interstitium of the trapezius muscle of women with chronic widespread pain and chronic neck-shoulder pain correlate with pain intensity and sensitivity. | Ghafouri, N., et al. 2013. Pain. 154: 1649-1658. PMID: 23707281
- Effects of two different specific neck exercise interventions on palmitoylethanolamide and stearoylethanolamide concentrations in the interstitium of the trapezius muscle in women with chronic neck shoulder pain. | Ghafouri, N., et al. 2014. Pain Med. 15: 1379-89. PMID: 24995488
- Association Between Plasma N-Acylethanolamides and High Hemoglobin Concentration in Southern Peruvian Highlanders. | Alarcón-Yaquetto, DE., et al. 2017. High Alt Med Biol. 18: 322-329. PMID: 28665150
- Bioactive lipids ALIAmides differentially modulate inflammatory responses of distinct subsets of primary human T lymphocytes. | Chiurchiù, V., et al. 2018. FASEB J. 32: 5716-5723. PMID: 29879374
- Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother's Milk Are Strongly Associated with Infant Weight at Four Months of Age-Data from the Odense Child Cohort. | Bruun, S., et al. 2018. Nutrients. 10: PMID: 30428553
- Stearoylethanolamide interferes with retrograde endocannabinoid signalling and supports the blood-brain barrier integrity under acute systemic inflammation. | Kasatkina, LA., et al. 2020. Biochem Pharmacol. 174: 113783. PMID: 31881191
- Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice. | Dubuc, I., et al. 2022. Front Immunol. 13: 893792. PMID: 35812400
- Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes. | Tomofuji, Y., et al. 2023. Commun Med (Lond). 3: 5. PMID: 36624208
- Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | Di Marzo, V., et al. 1996. Biochem J. 316 (Pt 3): 977-84. PMID: 8670178
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stearoyl Ethanolamide, 5 mg | sc-205515 | 5 mg | $85.00 | |||
Stearoyl Ethanolamide, 10 mg | sc-205515A | 10 mg | $153.00 |