Squalene (CAS 111-02-4)
See product citations (1)
QUICK LINKS
Squalene, a naturally occurring triterpene, plays a pivotal role in the biosynthesis of sterols, serving as a critical precursor in the synthesis of cholesterol, steroid hormones, and vitamin D in organisms. Its mechanism of action involves its participation in the sterol synthesis pathway, where it undergoes a series of enzymatic conversions, starting with its cyclization to lanosterol, which marks the beginning of a complex transformation process leading to the formation of various sterols. In research, squalene′s significance extends beyond its biological role, as it is utilized in studies aimed at understanding lipid metabolism and the regulation of cholesterol synthesis. Additionally, its involvement in the production of adjuvants for vaccines highlights its importance in the development of technologies aimed at enhancing immune responses, thereby providing a critical tool for researchers exploring novel vaccination strategies and the enhancement of immune system functioning.
Squalene (CAS 111-02-4) References
- Squalene emulsions for parenteral vaccine and drug delivery. | Fox, CB. 2009. Molecules. 14: 3286-312. PMID: 19783926
- Squalene: A natural triterpene for use in disease management and therapy. | Reddy, LH. and Couvreur, P. 2009. Adv Drug Deliv Rev. 61: 1412-26. PMID: 19804806
- Increased squalene concentrations in the clitoral gland during the estrous cycle in rats: an estrus-indicating scent mark? | Achiraman, S., et al. 2011. Theriogenology. 76: 1676-83. PMID: 21924481
- Biological importance and applications of squalene and squalane. | Kim, SK. and Karadeniz, F. 2012. Adv Food Nutr Res. 65: 223-33. PMID: 22361190
- Formulated squalene for food related applications. | Naziri, E. and Tsimidou, MZ. 2013. Recent Pat Food Nutr Agric. 5: 83-104. PMID: 23270393
- Methods for obtaining and determination of squalene from natural sources. | Popa, O., et al. 2015. Biomed Res Int. 2015: 367202. PMID: 25695064
- [SQUALENE: PHYSIOLOGICAL AND PHARMACOLOGICAL PROPERTIES]. | Muzalevskaya, EN., et al. 2015. Eksp Klin Farmakol. 78: 30-6. PMID: 26292512
- Advances in Biochemistry and Microbial Production of Squalene and Its Derivatives. | Ghimire, GP., et al. 2016. J Microbiol Biotechnol. 26: 441-51. PMID: 26643964
- Squalene isolated from Schizochytrium mangrovei is a peroxisome proliferator-activated receptor-α agonist that regulates lipid metabolism in HepG2 cells. | Hoang, TM., et al. 2016. Biotechnol Lett. 38: 1065-71. PMID: 26956235
- A gas chromatography-mass spectrometry method for quantifying squalane and squalene in aerosol emissions of electronic cigarette, or vaping, products. | Cowan, EA., et al. 2022. Talanta. 238: 122985. PMID: 34857320
- Assessment of squalene variability and its enhancement in Amaranthus (Amaranthus caudatus L.) populations: With application to vaccine development. | Verma, KC. 2022. Biotechnol Appl Biochem. 69: 2745-2752. PMID: 35032134
- Dietary squalene supplementation decreases triglyceride species and modifies phospholipid lipidomic profile in the liver of a porcine model of non-alcoholic steatohepatitis. | Herrera-Marcos, LV., et al. 2023. J Nutr Biochem. 112: 109207. PMID: 36402249
- Candida glycerinogenes-Promoted α-Pinene and Squalene Co-production Strategy Based on α-Pinene Stress. | Ma, T., et al. 2023. J Agric Food Chem. 71: 5250-5260. PMID: 36971258
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Squalene, 10 ml | sc-281155 | 10 ml | $48.00 | |||
Squalene, 100 ml | sc-281155A | 100 ml | $90.00 | |||
Squalene, 500 ml | sc-281155B | 500 ml | $211.00 |