Date published: 2025-11-4

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Spinosad (CAS 168316-95-8)

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Application:
Spinosad is a reference standard
CAS Number:
168316-95-8
Molecular Weight:
1477.93
Molecular Formula:
C83H132N2O20
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Spinosad is an analytical, chromatography and environmental standard. Spinosad is an insecticide found in the soil bacterium S. spinosa. It consists of a blend of two macrocyclic lactones, spinosyn A and spinosyn D. These compounds function as agonists, binding to insect nicotinic acetylcholinesterase receptors (nAChRs). It undergoes rapid degradation in the environment, resulting in its limited persistence in the soil over extended durations.


Spinosad (CAS 168316-95-8) References

  1. A review of spinosad as a natural product for larval mosquito control.  |  Hertlein, MB., et al. 2010. J Am Mosq Control Assoc. 26: 67-87. PMID: 20402353
  2. High Level of Spinosad Production in the Heterologous Host Saccharopolyspora erythraea.  |  Huang, J., et al. 2016. Appl Environ Microbiol. 82: 5603-11. PMID: 27401975
  3. Spinosad induces autophagy of Spodoptera frugiperda Sf9 cells and the activation of AMPK/mTOR signaling pathway.  |  Yang, M., et al. 2017. Comp Biochem Physiol C Toxicol Pharmacol. 195: 52-59. PMID: 28223193
  4. Spinosad-mediated effects on the walking ability, midgut, and Malpighian tubules of Africanized honey bee workers.  |  Lopes, MP., et al. 2018. Pest Manag Sci. 74: 1311-1318. PMID: 29194936
  5. Strategies for Enhancing the Yield of the Potent Insecticide Spinosad in Actinomycetes.  |  Tao, H., et al. 2019. Biotechnol J. 14: e1700769. PMID: 29897659
  6. Cytotoxic effects of bio-pesticide spinosad on human lung A549 cells.  |  Zhang, Y., et al. 2019. Chemosphere. 230: 182-189. PMID: 31103864
  7. Biopesticide spinosad induces transcriptional alterations in genes associated with energy production in honey bees (Apis mellifera) at sublethal concentrations.  |  Christen, V., et al. 2019. J Hazard Mater. 378: 120736. PMID: 31202068
  8. Properties, toxicity and current applications of the biolarvicide spinosad.  |  Santos, VSV. and Pereira, BB. 2020. J Toxicol Environ Health B Crit Rev. 23: 13-26. PMID: 31709913
  9. Spinosad application in an apple orchard affects both the abundance of the spider Araneus diadematus and its web construction behaviour.  |  Mazzia, C., et al. 2020. Ecotoxicology. 29: 389-397. PMID: 32274624
  10. New insights on the effects of spinosad on the development of Helicoverpa armigera.  |  Yao, S., et al. 2021. Ecotoxicol Environ Saf. 221: 112452. PMID: 34198186
  11. Spinosad resistance in field populations of melon fly, Zeugodacus cucurbitae (Coquillett), in Hawaii.  |  Hsu, JC., et al. 2021. Pest Manag Sci. 77: 5439-5444. PMID: 34331843
  12. Multiplying the heterologous production of spinosad through tandem amplification of its biosynthetic gene cluster in Streptomyces coelicolor.  |  Li, H., et al. 2022. Microb Biotechnol. 15: 1550-1560. PMID: 34796664
  13. Effects of Temephos (Abate®), Spinosad (Natular®), and Diflubenzuron on the Survival of Cyclopoid Copepods.  |  Grunert, R., et al. 2022. Am J Trop Med Hyg. 106: 818-822. PMID: 35073509
  14. Spatio-temporal Variation of Spinosad Susceptibility in Drosophila suzukii (Diptera: Drosophilidae), a Three-year Study in California's Monterey Bay Region.  |  Ganjisaffar, F., et al. 2022. J Econ Entomol. 115: 972-980. PMID: 35137165
  15. Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies.  |  Martelli, F., et al. 2022. Elife. 11: PMID: 35191376

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Spinosad, 100 mg

sc-396638
100 mg
$220.00