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Sorbitan monolaurate (CAS 1338-39-2)

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Alternate Names:
Span® 20
Application:
Sorbitan monolaurate is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol
CAS Number:
1338-39-2
Molecular Weight:
346.46
Molecular Formula:
C18H34O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sorbitan monolaurate is a compound that is widely utilized in research related to its surfactant properties. It is a nonionic surfactant that is amphiphilic, allowing it to reduce surface tension between various phases. In research, sorbitan monolaurate is often used to stabilize emulsions and as a dispersing agent for suspensions. Studies involving this compound include investigating its effects on the stabilization of lipid bilayers and liposomes. Additionally, its role in modifying the surface properties of materials is explored in the development of coatings and formulations. The compound′s interactions with proteins and its application in bioseparation processes are also of significant interest, contributing to advancements in analytical and preparative biochemical techniques.


Sorbitan monolaurate (CAS 1338-39-2) References

  1. Rheological properties of three component creams containing sorbitan monoesters as surfactants.  |  Korhonen, M., et al. 2002. Int J Pharm. 247: 103-14. PMID: 12429489
  2. Synergistic effects of chemical enhancers on skin permeability: a case study of sodium lauroylsarcosinate and sorbitan monolaurate.  |  Karande, P., et al. 2007. Eur J Pharm Sci. 31: 1-7. PMID: 17368869
  3. The effect of different ethoxylations for sorbitan monolaurate on enhancing simultaneous saccharification and fermentation (SSF) of wheat straw to ethanol.  |  Badawi, AM., et al. 2012. Appl Biochem Biotechnol. 166: 22-35. PMID: 21984384
  4. Role of SULT-mediated sulfation in the biotransformation of 2-butoxyethanol and sorbitan monolaurate: A study using zebrafish SULTs.  |  Xi, Y., et al. 2016. Aquat Toxicol. 177: 19-21. PMID: 27218426
  5. Development and in-vitro characterization of sorbitan monolaurate and poloxamer 184 based niosomes for oral delivery of diacerein.  |  Khan, MI., et al. 2016. Eur J Pharm Sci. 95: 88-95. PMID: 27600819
  6. Re-evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives.  |  , ., et al. 2017. EFSA J. 15: e04788. PMID: 32625491
  7. Safety and efficacy of sorbitan monolaurate as a feed additive for all animal species.  |  , ., et al. 2019. EFSA J. 17: e05651. PMID: 32626271
  8. Safety for the environment of sorbitan monolaurate as a feed additive for all animal species.  |  , ., et al. 2020. EFSA J. 18: e06162. PMID: 32874337
  9. Biocompatible Ionic Liquid-Mediated Micelles for Enhanced Transdermal Delivery of Paclitaxel.  |  Ali, MK., et al. 2021. ACS Appl Mater Interfaces. 13: 19745-19755. PMID: 33891816
  10. Improved Bioavailability of Ebastine through Development of Transfersomal Oral Films.  |  Islam, N., et al. 2021. Pharmaceutics. 13: PMID: 34452276
  11. Optimization of PAHs oxidation from contaminated soil using modified nanoscale zero-valent iron combined with potassium permanganate.  |  Sun, X., et al. 2022. RSC Adv. 12: 7335-7346. PMID: 35424712
  12. Polysorbate 21 Can Modulate the Antibacterial Potential of Two Pyrazol Derivatives.  |  Aonofriesei, F. 2022. Biomolecules. 12: PMID: 36551246
  13. Demulsification of water-in-oil emulsions stabilized with glycerol monostearate crystals.  |  El-Aooiti, M., et al. 2023. J Colloid Interface Sci. 636: 637-645. PMID: 36680954
  14. Short-term toxicity study of sorbitan monolaurate (Span 20) in rats.  |  Cater, BR., et al. 1978. Food Cosmet Toxicol. 16: 519-26. PMID: 730078
  15. The composition of NF-defined emulsifiers: sorbitan monolaurate, monopalmitate, monostearate, monooleate, polysorbate 20, polysorbate 40, polysorbate 60, and polysorbate 80.  |  Brandner, JD. 1998. Drug Dev Ind Pharm. 24: 1049-54. PMID: 9876559

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sorbitan monolaurate, 250 g

sc-281151
250 g
$51.00

Sorbitan monolaurate, 1 kg

sc-281151A
1 kg
$141.00