Sodium Pyruvate An intermediate of sugar metabolism, an antioxidant, and an apoptosis inhibitor

Sodium Pyruvate (CAS 113-24-6)

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Synonym: Pyruvic Acid Sodium Salt; α-Ketopropionic acid sodium salt; 2-Oxopropanoic acid sodium salt
Application: An intermediate of sugar metabolism, an antioxidant, and an apoptosis inhibitor
CAS Number: 113-24-6
Molecular Weight: 110.04
Molecular Formula: C3H3O3•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sodium Pyruvate (Pyruvic Acid Sodium Salt) is an intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscles, pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion. It is a free radical scavenger and has been shown to protect against hydrogen peroxide mediated apoptosis.


References

1. Thompson, S.N. 2000. Biochem. Biophys. Res. Commun. 274: 787-793. PMID: 10924355
2. Joseph-Horne, T., et al. 2000. FEBS Lett. 481: 141-146. PMID: 10996313
3. Zhao, W., et al. 2000. Free Radic. Res. 33: 23-30. PMID: 10826918
4. Miwa, H., et al. 2000. Free Radic. Res. 33: 45-56. PMID: 10826920
5. Alexeeva, S., et al. 2000. J. Bacteriol. 182: 4934-4940. PMID: 10940038
6. Nemoto, S., et al. 2000. Mol. Cell. Biol. 20: 7311-7318. PMID: 10982848
7. Li, Y., et al. 2000. Sheng Wu Gong Cheng Xue Bao. 16: 225-228. PMID: 10976333

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (100 mg/ml).
Storage :
Store at 4° C
Melting Point :
>300° C (lit.)
Refractive Index :
n20D ~1.42 (Predicted)
Ki Data :
CA IV: Ki= 14.5 µM (human); Carbonic anhydrase: Ki= 105.7 µM (Candida albicans ); CA IX: Ki= 1.12 mM (human); CA II: Ki= 2.11 mM (human); CA V: Ki= 5.5 mM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
23662274
MDL Number :
MFCD00002586
EC Number :
204-024-4
Beilstein Registry :
3568341
SMILES :
CC(=O)C(=O)[O-].[Na+]

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Sodium Pyruvate  Product Citations

See how others have used Sodium Pyruvate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 28223427  Noguchi, F. et al. 2017. Mol. Cancer Ther. 16: 936-947.

Citations 1 to 1 of 1 total
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