Sodium Pyruvate (Pyruvic Acid Sodium Salt) is an intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscles, pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion. It is a free radical scavenger and has been shown to protect against hydrogen peroxide mediated apoptosis.
1. Thompson, S.N. 2000. Biochem. Biophys. Res. Commun. 274: 787-793. PMID: 10924355 2. Joseph-Horne, T., et al. 2000. FEBS Lett. 481: 141-146. PMID: 10996313 3. Zhao, W., et al. 2000. Free Radic. Res. 33: 23-30. PMID: 10826918 4. Miwa, H., et al. 2000. Free Radic. Res. 33: 45-56. PMID: 10826920 5. Alexeeva, S., et al. 2000. J. Bacteriol. 182: 4934-4940. PMID: 10940038 6. Nemoto, S., et al. 2000. Mol. Cell. Biol. 20: 7311-7318. PMID: 10982848 7. Li, Y., et al. 2000. Sheng Wu Gong Cheng Xue Bao. 16: 225-228. PMID: 10976333
Soluble in water (100 mg/ml).
Store at 4° C
>300° C (lit.)
n20D ~1.42 (Predicted)
CA IV: Ki= 14.5 µM (human); Carbonic anhydrase: Ki= 105.7 µM (Candida albicans ); CA IX: Ki= 1.12 mM (human); CA II: Ki= 2.11 mM (human); CA V: Ki= 5.5 mM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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