Date published: 2025-9-18

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Sodium hydroxymethanesulfinate (CAS 149-44-0)

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Alternate Names:
Hydroxymethanesulfinic acid sodium salt; Sodium formaldehyde sulfoxylate
Application:
Sodium hydroxymethanesulfinate is an organic reductant
CAS Number:
149-44-0
Molecular Weight:
118.09
Molecular Formula:
CH3NaO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium hydroxymethanesulfinate hydrate functions as a reducing agent in chemical reactions, in the reduction of carbonyl compounds to their corresponding alcohols. It acts by donating a hydrogen atom to the carbonyl group, leading to the formation of a hydroxyl group and the reduction of the carbonyl compound. Sodium Hydroxymethanesulfinate Hydrate′s mechanism of action involves the transfer of a hydride ion to the carbonyl carbon, resulting in the formation of a new C-H bond and the conversion of the carbonyl group into a hydroxyl group. This process occurs through a nucleophilic addition mechanism, where the hydride ion attacks the electrophilic carbon of the carbonyl group, leading to the reduction reaction. Sodium hydroxymethanesulfinate hydrate plays a functional role in facilitating the synthesis of alcohols from carbonyl compounds, contributing to the understanding of organic chemical reactions and the development of new methodologies.


Sodium hydroxymethanesulfinate (CAS 149-44-0) References

  1. Reactive oxygen species in the aerobic decomposition of sodium hydroxymethanesulfinate.  |  Makarov, SV., et al. 1999. Arch Biochem Biophys. 367: 289-96. PMID: 10395746
  2. Chemistry of trichlorofluoromethane: synthesis of chlorofluoromethyl phenyl sulfone and fluoromethyl phenyl sulfone and some of their reactions.  |  Saikia, AK. and Tsuboi, S. 2001. J Org Chem. 66: 643-7. PMID: 11430077

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium hydroxymethanesulfinate, 500 g

sc-236907
500 g
$51.00