Date published: 2025-11-20

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Sesamolin (CAS 526-07-8)

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Application:
Sesamolin is Sesamolin inhibited lipid peroxidation in rat liver and kidney
CAS Number:
526-07-8
Molecular Weight:
370.36
Molecular Formula:
C20H18O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sesamolin is a lignan compound widely studied in agricultural and food science research. It is found in sesame seeds and sesame oil and is of interest for its potential in protecting oils from rancidity due to its antioxidant properties. In plant biology, sesamolin is investigated for its role in the defense mechanisms of the sesame plant against environmental stressors. Researchers also explore its impact on the nutritional quality and shelf life of food products, as well as its potential use as a natural preservative. Additionally, sesamolin is a subject of study in the field of organic chemistry, where scientists examine its chemical structure to understand the synthesis and reactivity of lignan compounds. Environmental studies may also look into the biodegradation of sesamolin and its byproducts to assess its behavior and fate in natural ecosystems.


Sesamolin (CAS 526-07-8) References

  1. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia.  |  Cheng, FC., et al. 2006. Int J Biomed Sci. 2: 284-8. PMID: 23674992
  2. Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt's lymphoma cells.  |  Kim, JH. and Lee, JK. 2015. Int Immunopharmacol. 28: 977-84. PMID: 26298637
  3. Sesamin and sesamolin reduce amyloid-β toxicity in a transgenic Caenorhabditis elegans.  |  Keowkase, R., et al. 2018. Biomed Pharmacother. 107: 656-664. PMID: 30118882
  4. Sesamolin affects both natural killer cells and cancer cells in order to create an optimal environment for cancer cell sensitization.  |  Lee, SE. and Lee, JK. 2018. Int Immunopharmacol. 64: 16-23. PMID: 30144640
  5. Using Turmeric Oil as a Solvent Improves the Distribution of Sesamin-Sesamolin in the Serum and Brain of Mice.  |  Iwamoto, K., et al. 2019. Lipids. 54: 311-320. PMID: 30993746
  6. Sesamolin exerts anti-proliferative and apoptotic effect on human colorectal cancer cells via inhibition of JAK2/STAT3 signaling pathway.  |  Wu, D., et al. 2019. Cell Mol Biol (Noisy-le-grand). 65: 96-100. PMID: 31472054
  7. Inhibitory Effect of Sesamolin on Melanogenesis in B16F10 Cells Determined by In Vitro and Molecular Docking Analyses.  |  Baek, SH., et al. 2020. Curr Pharm Biotechnol. 21: 169-178. PMID: 31612825
  8. Sesamolin promotes cytolysis and migration activity of natural killer cells via dendritic cells.  |  Lee, JK. 2020. Arch Pharm Res. 43: 462-474. PMID: 32279231
  9. Formation of Samin Diastereomers by Acid-Catalyzed Transformation of Sesamolin with Hydrogen Peroxide.  |  Tsai, HY., et al. 2020. J Agric Food Chem. 68: 6430-6438. PMID: 32396352
  10. Sesamolin Protects Mice From Ovariectomized Bone Loss by Inhibiting Osteoclastogenesis and RANKL-Mediated NF-κB and MAPK Signaling Pathways.  |  Yang, X., et al. 2021. Front Pharmacol. 12: 664697. PMID: 34194327
  11. Route of intracellular uptake and cytotoxicity of sesamol, sesamin, and sesamolin in human melanoma SK-MEL-2 cells.  |  Srisongkram, T. and Weerapreeyakul, N. 2022. Biomed Pharmacother. 146: 112528. PMID: 34906777
  12. Developmental effects of sesamolin on zebrafish (Danio rerio) embryos.  |  Kitipaspallop, W., et al. 2022. Comp Biochem Physiol C Toxicol Pharmacol. 256: 109319. PMID: 35227877
  13. Comparative effects of sesame lignans (sesamin, sesamolin, and sesamol) on oxidative stress and lipid metabolism in steatosis HepG2 cells.  |  Shi, L., et al. 2022. J Food Biochem. 46: e14180. PMID: 35396857
  14. Sesamolin Alleviates Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites in High-Fat and High-Fructose Diet-Fed Mice.  |  Yu, J., et al. 2022. Int J Mol Sci. 23: PMID: 36430326
  15. Sesamolin Attenuates Kidney Injury, Intestinal Barrier Dysfunction, and Gut Microbiota Imbalance in High-Fat and High-Fructose Diet-Fed Mice.  |  Yang, Y., et al. 2023. J Agric Food Chem. 71: 1562-1576. PMID: 36630317

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sesamolin, 10 mg

sc-490301
10 mg
$350.00