Molecular structure of Sesamol, CAS Number: 533-31-3
Sesamol (CAS 533-31-3)
Alternate Names:
5-Hydroxy-1,3-benzodioxole; 3,4-(Methylenedioxy)phenol
CAS Number:
533-31-3
Purity:
≥97%
Molecular Weight:
138.12
Molecular Formula:
C7H6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sesamol is a compound that functions as an antioxidant in experimental applications. It exerts its mechanism of action by scavenging free radicals and inhibiting oxidative stress at the molecular level. Sesamol is known to interact with reactive oxygen species, preventing cellular damage and lipid peroxidation. Sesamol has been observed to modulate various signaling pathways involved in oxidative stress, thereby contributing to the maintenance of cellular homeostasis. Its ability to chelate metal ions also plays a role in its antioxidant function, further enhancing its protective effects against oxidative damage.
Sesamol (CAS 533-31-3) References
- Sesamol Alleviates Airway Hyperresponsiveness and Oxidative Stress in Asthmatic Mice. | Liou, CJ., et al. 2020. Antioxidants (Basel). 9: PMID: 32244835
- Sesamol Increases Ucp1 Expression in White Adipose Tissues and Stimulates Energy Expenditure in High-Fat Diet-Fed Obese Mice. | Lee, DH., et al. 2020. Nutrients. 12: PMID: 32443555
- Alkylated Sesamol Derivatives as Potent Antioxidants. | C Palheta, I., et al. 2020. Molecules. 25: PMID: 32708143
- Preparations and antioxidant activities of sesamol and it's derivatives. | Zhou, S., et al. 2021. Bioorg Med Chem Lett. 31: 127716. PMID: 33249134
- Sesamol induces cytotoxicity via mitochondrial apoptosis in SCC-25 cells. | Ezhilarasan, D., et al. 2021. Hum Exp Toxicol. 40: S423-S433. PMID: 34586880
- Sesamol ameliorates hepatic lipid accumulation and oxidative stress in steatosis HepG2 cells via the PPAR signaling pathway. | Shi, L., et al. 2021. J Food Biochem. 45: e13976. PMID: 34664288
- Sesamol Attenuates Amyloid Peptide Accumulation and Cognitive Deficits in APP/PS1 Mice: The Mediating Role of the Gut-Brain Axis. | Liu, Q., et al. 2021. J Agric Food Chem. 69: 12717-12729. PMID: 34669408
- Sesamol Ameliorates Renal Injury-Mediated Atherosclerosis via Inhibition of Oxidative Stress/IKKα/p53. | Wang, JS., et al. 2021. Antioxidants (Basel). 10: PMID: 34679653
- Sesamol Induces Apoptosis-Like Cell Death in Leishmania donovani. | Ali, R., et al. 2021. Front Cell Infect Microbiol. 11: 749420. PMID: 34778106
- Sesamol Attenuates Neuroinflammation by Regulating the AMPK/SIRT1/NF-κB Signaling Pathway after Spinal Cord Injury in Mice. | Feng, X., et al. 2022. Oxid Med Cell Longev. 2022: 8010670. PMID: 35035666
- Sesamol Reverses Myofiber-Type Conversion in Obese States via Activating the SIRT1/AMPK Signal Pathway. | Hu, MM., et al. 2022. J Agric Food Chem. 70: 2253-2264. PMID: 35166533
- Sesamol Augments Paclitaxel-Induced Apoptosis in Human Cervical Cancer Cell Lines. | Xiong, J., et al. 2022. Nutr Cancer. 74: 3692-3700. PMID: 35639488
- Sesamol Attenuates Scopolamine-Induced Cholinergic Disorders, Neuroinflammation, and Cognitive Deficits in Mice. | Yun, D., et al. 2022. J Agric Food Chem. 70: 13602-13614. PMID: 36239029
- Sesamol inhibits proliferation, migration and invasion of triple negative breast cancer via inactivating Wnt/β-catenin signaling. | Ma, X., et al. 2022. Biochem Pharmacol. 206: 115299. PMID: 36244446
- Sesamol improves bone mass in ovary intact growing and adult rats but accelerates bone deterioration in the ovariectomized rats. | Patel, K., et al. 2023. J Nutr Biochem. 119: 109384. PMID: 37209954
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sesamol, 5 g | sc-253552 | 5 g | $28.00 |