Molecular structure of Sericic acid
Sericic acid (CAS 55306-03-1)
Alternate Names:
2,3,19,23-Tetrahydroxyolean-12-en-28-oic acid
Application:
Sericic acid is an antioxidant, PDE4A inhibitor, antiinflammatory, antifungal, and antibacterial
CAS Number:
55306-03-1
Molecular Weight:
504.70
Molecular Formula:
C30H48O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sericic acid is an antioxidant that serves as a weak PDE4A inhibitor, antiinflammatory, antifungal, and antibacterial. Sericic acid, extracted from the Bombyx mori silkworm, is a naturally occurring protein that exhibits water solubility. With its inherent antibacterial characteristics and capacity to enhance cell adhesion and proliferation, sericic acid has garnered significant interest as a potential scaffold material for tissue engineering applications. It is hypothesized that sericic acid exerts its effects by binding to cellular membranes, inducing alterations in their structure, and subsequently modulating various cell signaling pathways. Furthermore, sericic acid has demonstrated interactions with enzymes and receptors, which may influence the expression of genes associated with cellular proliferation and differentiation.
Sericic acid (CAS 55306-03-1) References
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- Norsesquiterpenoids and triterpenoids from strawberry cv. Falandi. | Yang, D., et al. 2016. Food Chem. 203: 67-72. PMID: 26948590
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- Genotoxic and Chemopreventive Effects of Vochysia divergens Leaves (Pantanal, Brazil). | de Oliveira, PF., et al. 2018. Evid Based Complement Alternat Med. 2018: 6596142. PMID: 30327680
- Protoflavanones from the Wood Stem of Salvertia convallariodora. | De Mesquita, ML., et al. 2017. Nat Prod Commun. 12: 515-518. PMID: 30520585
- American Civil War plant medicines inhibit growth, biofilm formation, and quorum sensing by multidrug-resistant bacteria. | Dettweiler, M., et al. 2019. Sci Rep. 9: 7692. PMID: 31118466
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- Phytochemical Profiling and Quality Control of Terminalia sericea Burch. ex DC. Using HPTLC Metabolomics. | Mulaudzi, N., et al. 2021. Molecules. 26: PMID: 33467662
- Sericic Acid Ameliorates DSS-induced Ulcerative Colitis in Mice by Modulating the NF-κB and Nrf2 Pathways. | Lifei-Luo, ., et al. 2023. Curr Mol Pharmacol. 16: 759-770. PMID: 36173058
- Anti-Candida Activity of Extracts Containing Ellagitannins, Triterpenes and Flavonoids of Terminalia brownii, a Medicinal Plant Growing in Semi-Arid and Savannah Woodland in Sudan. | Salih, EYA., et al. 2022. Pharmaceutics. 14: PMID: 36432659
- An integrated strategy for quality control of the multi-origins herb medicine of Gentianae Macrophyllae Radix based on UPLC-Orbitrap-MS/MS and HPLC-DAD. | Luo, J., et al. 2023. RSC Adv. 13: 8847-8862. PMID: 36936846
- Antibacterial activity and phytochemical analysis of Vochysia divergens (Vochysiaceae). | Hess, SC., et al. 1995. J Ethnopharmacol. 47: 97-100. PMID: 7500642
Inhibitor of:
PDE4A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sericic acid, 5 mg | sc-396534 | 5 mg | $122.00 | |||
Sericic acid, 25 mg | sc-396534A | 25 mg | $490.00 |